Fungal peritonitis in Iranian children on continuous ambulatory peritoneal dialysis: a national experience.

Hooman, N. and Madani, A. and Sharifian Dorcheh, M. and Mahdavi, A. and Derakhshan, A. and Gheissari, A. and Esfahani, S.T. and Otukesh, H. and Mohkam, M. and Falahzadeh, M.H. and Hosseini Al Hashemi, G. and Azir, A. and Merikhi, A. and Golikhani, F. and Latif, E. and Karimi, S. and Zakavat, T. and Mohseni, P. and Ataei, N. and Nickavar, A. and Basiratnia, M. (2007) Fungal peritonitis in Iranian children on continuous ambulatory peritoneal dialysis: a national experience. Iranian journal of kidney diseases, 1 (1). pp. 29-33.

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INTRODUCTION. Fungal peritonitis (FP), causing catheter obstruction, dialysis failure, and peritoneal dysfunction, is a rare but serious complication of peritoneal dialysis. In this study, the frequency and risk factors of FP are evaluated in children who underwent peritoneal dialysis. MATERIALS AND METHODS. A retrospective multicenter study was performed at the 5 pediatric peritoneal dialysis centers in Iran from 1971 to 2006, and FP episodes among 93 children were reviewed. Risk ratios were calculated for the clinical and demographic variables to determine the risk factors of FP. RESULTS. Ninety-three children aged 39 months on average were included in study. Sixteen out of 155 episodes of peritonitis were fungi infections, all by Candida albicans. The risk of FP was higher in those with relapsing bacterial peritonitis (P = .009). Also, all of the patients had received antibiotics within the 1 month prior to the development of FP. Catheters were removed in all patients after 1 to 7 days of developing FP. Six out of 12 patients had catheter obstruction and peritoneal loss after the treatment and 5 died due to infection. CONCLUSIONS. Fungal peritonitis, accompanied by high morbidity and mortality in children should be reduced by prevention of bacterial peritonitis. Early removal of catheter after recognition of FP should be considered.

Item Type: Article
Additional Information: cited By 8
Uncontrolled Keywords: article; Candida albicans; candidiasis; child; chronic kidney failure; clinical trial; cohort analysis; continuous ambulatory peritoneal dialysis; female; human; indwelling catheter; infant; Iran; male; microbiology; multicenter study; peritonitis; preschool child; retrospective study; survival rate, Candida albicans; Candidiasis; Catheters, Indwelling; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Iran; Kidney Failure, Chronic; Male; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Retrospective Studies; Survival Rate
Subjects: WJ Urogenital System
WS Pediatrics
Divisions: School of Rehabilitation Sciences
Depositing User: parto mrs bakhtminoo
Date Deposited: 26 Feb 2019 10:36
Last Modified: 26 Feb 2019 10:36

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