Evaluation of antioxidant activity of methanolic extracts and some fractions of Salvia verticillata L. using three different methods

Souri, E. and Farsam, H. and Ardestani, S. and Zolfagharifar, M. (2007) Evaluation of antioxidant activity of methanolic extracts and some fractions of Salvia verticillata L. using three different methods. Journal of Medicinal Plants, 6 (21). 20-25+3.

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Abstract

Background: Bradykinin has effects on histaminic response,vessels seepage,cellular reproduction,causing fever, pain and coughs caused by ACE controllers (3,4,6). Noscapin has controlled Bradykinins contractional effects on guinea pigs trachea and rats vazodofran (5,6). noscapin stops the secondary effects of eskimi in brains edema, with antagonizing the responses caused by Bradykinin (3,4,8). Objective: considering that opium's alkaloids act as agonist of peptide systems like ankephalins and RAS, its interesting to know the effects of this alkaloids and among them Noscapine on B3 Bradykinin receptors on smooth muscle guinea pig trachea? Method: All variables are reported as mean and standard deviation. We have used pair test and the informations were processed by Excel, Statistical analysis with ANOVA (LSD) SPSS 9. Results: we took diagrams in to consideration and indicated that the contract ional effect of Bradykinin decreased dependent on density, in presence of three different amount of noscapines concentration. In this study we could demonstrate that noscapine interact with Bradykenin as a non competitive antagonist.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: bradykinin receptor; enkephalin; histamine; indometacin; methanol; noscapine; opiate; plant extract; Salvia verticillata extract; unclassified drug, analysis of variance; animal experiment; antioxidant activity; article; controlled study; drug binding; drug effect; guinea pig; nonhuman; Salvia; salvia verticillata; smooth muscle; trachea muscle, Cavia; Rattus; Salvia verticillata
Subjects: QV Pharmacology
Divisions: School of Rehabilitation Sciences
Depositing User: parto mrs bakhtminoo
Date Deposited: 26 Feb 2019 11:15
Last Modified: 26 Feb 2019 11:15
URI: http://eprints.iums.ac.ir/id/eprint/12245

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