Burden of diarrhea in the Eastern Mediterranean Region, 1990�2015: Findings from the Global Burden of Disease 2015 study

Mokdad, A.H. and Khalil, I. and El Bcheraoui, C. and Charara, R. and Moradi-Lakeh, M. and Afshin, A. and Kassebaum, N.J. and Collison, M. and Chew, A. and Krohn, K.J. and Daoud, F. and Colombara, D. and Foreman, K.J. and Godwin, W.W. and Kutz, M. and Mirarefin, M. and Rao, P.C. and Reiner R., Jr. and Troeger, C. and Wang, H. and Niguse Abraha, H. and Abu-Elyazeed, R. and Abu-Raddad, L.J. and Ahmad Kiadaliri, A. and Ahmadi, A. and Beshir Ahmed, M. and Alam, K. and Alizadeh-Navaei, R. and Al-Raddadi, R. and Altirkawi, K.A. and Alvis-Guzman, N. and Anber, N. and Anwari, P. and Mehari Atey, T. and Arthur Avokpaho, E.F.G. and Bacha, U. and Bazargan-Hejazi, S. and Bedi, N. and Bensenor, I.M. and Berhane, A. and Obong Bessong, P. and Shunu Beyene, A. and Bhutta, Z.A. and Colin Buckle, G. and Butt, Z.A. and Danawi, H. and Deribew, A. and Djalalinia, S. and Dubey, M. and Yesuf Endries, A. and Eshrati, B. and Fereshtehnejad, S.-M. and Fischer, F. and Tewelde Gebrehiwot, T. and Chander Gugnani, H. and Ribhi Hamadeh, R. and Hamidi, S. and Husseini, A. and James, S.L. and Jonas, J.B. and Kasaeian, A. and Saleh Khader, Y. and Ahmad Khan, E. and Khan, G. and Khubchandani, J. and Kissoon, N. and Kopec, J.A. and Koyanagi, A. and Kuate Defo, B. and Larson, H.J. and Abdul Latif, A. and Lunevicius, R. and Abd El Razek, H.M. and Abd El Razek, M.M. and Majdzadeh, R. and Majeed, A. and Malekzadeh, R. and Memiah, P. and Memish, Z.A. and Mendoza, W. and Tadese Mengistu, D. and Mohammed, S. and Murthy, S. and Wanjiku Ngunjiri, J. and Akpojene Ogbo, F. and Pourmalek, F. and Qorbani, M. and Radfar, A. and Rafay, A. and Rahimi-Movaghar, V. and Kumar Rai, R. and Ram, U. and Laith Rawaf, D. and Rawaf, S. and Renzaho, A.M.N. and Rezaei, S. and Roshandel, G. and Safdarian, M. and Ali Sahraian, M. and Salamati, P. and Samy, A.M. and Ramon Sanabria, J. and Sartorius, B. and Sepanlou, S.G. and Ali Shaikh, M. and Shigematsu, M. and Sobaih, B.H.A. and Sreeramareddy, C.T. and Sykes, B.L. and Tehrani-Banihashemi, A. and Temsah, M.-H. and Sulieman Terkawi, A. and Yimer Tiruye, T. and Topor-Madry, R. and Nnanna Ukwaja, K. and Emil Vollset, S. and Wakayo, T. and Werdecker, A. and Shey Wiysonge, C. and Workicho, A. and Yaghoubi, M. and Yaseri, M. and Yenesew, M. and Yonemoto, N. and Younis, M.Z. and El Sayed Zaki, M. and Zodpey, S. and Zein, B. and Jumaan, A.O. and Vos, T. and Hay, S.I. and Naghavi, M. and Murray, C.J.L. and Collaborators, GBD 2015 Eastern Mediterranean Region Diarrhea (2018) Burden of diarrhea in the Eastern Mediterranean Region, 1990�2015: Findings from the Global Burden of Disease 2015 study. International Journal of Public Health, 63. pp. 109-121.

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Abstract

Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children�s potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)�the sum of years of life lost and years lived with disability�for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95 uncertainty interval: 87,018�124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95 UI: 13.4�19.2). The majority of these deaths occurred in children under 5 (63.3) (65,670 deaths, 95 UI: 53,640�79,486). DALYs per 100,000 ranged from 304 (95 UI 228�400) in Kuwait to 38,900 (95 UI 25,900�54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden. © 2017, The Author(s).

Item Type: Article
Additional Information: cited By 2
Depositing User: eprints admin
Date Deposited: 05 Aug 2018 05:35
Last Modified: 05 Aug 2018 05:35
URI: http://eprints.iums.ac.ir/id/eprint/358

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