Potentiometric sensing of lamotrigine based on molecularly imprinted polymers

Sadeghi, H.B. and Ebrahimi, S.A. and Tamaddon, A. and Bozorgvar, F. and Afifinia, H. and Almasian, N. and Mollaei, S. (2011) Potentiometric sensing of lamotrigine based on molecularly imprinted polymers. Electroanalysis, 23 (11). pp. 2716-2723.

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Abstract

In the present work a novel potentiometric sensor, based on a noncovalent imprinted polymer, was developed for determination of Lamotrigine (LTG). At optimized conditions the electrode exhibited a Nernstian response (30.8±1.0mV decade-1) in a concentration range of 1�10-6 to 1�10-3M with a detection limit of 8�10-7mol L-1. The potential response of the electrode was constant in the pH range of 1.0-5.0. The electrode demonstrated a response time of ~30s. The selectivity coefficient of the sensor toward a number of different drugs with molecular similarities and some metal ions was evaluated. The electrode was examined for determination of LTG in real samples. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Item Type: Article
Additional Information: cited By 9
Depositing User: EPrints System Admin
Date Deposited: 19 Jul 2017 10:13
Last Modified: 19 Jul 2017 10:13
URI: http://eprints.iums.ac.ir/id/eprint/43

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