Evaluating the effects of administration of 25-hydroxyvitamin D supplement on serum anti-mullerian hormone (AMH) levels in infertile women

Naderi, Z. and Kashanian, M. and Chenari, L. and Sheikhansari, N. (2018) Evaluating the effects of administration of 25-hydroxyvitamin D supplement on serum anti-mullerian hormone (AMH) levels in infertile women. Gynecological Endocrinology, 34 (5). pp. 409-412.

Full text not available from this repository.
Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

The aim of the study was to evaluate the effects of administration of 25-hydroxyvitamin D 25(OH) D on serum antimullerian hormone (AMH) levels in infertile women. The study was performed as a non-randomized clinical trial on 30 infertile women who had low serum level of both 25(OH) D and anti-mullerian hormone. Vitamin D was prescribed 50,000 IU weekly for up to three months for all eligible participants. Serum levels of both 25(OH) D and AMH have increased significantly after treatment with 25(OH) D. There was a significant correlation between serum levels of 25(OH) D after treatment with AMH (p =.029, OR = 2.9, CI 95% = 2.7�5.5). Mean AMH level after treatment was higher in women with sufficient 25(OH) D, than women with insufficient 25(OH) D (1.048 ± 0.644 vs. 0.513 ± 0.284 ng/ml), which shows a significant difference (p =.043). Also, after treatment, in women with mean AMH level of >0.7 ng/ml (19 women), mean level of 25(OH) D was higher than in women with mean AMH level of <0.7 ng/ml (11 women) (59.332 ± 21.751 vs. 38.881 ± 17.281 ng/ml, p =.013). This means that higher levels of 25(OH) D are accompanied with higher levels of AMH. In conclusions with administration and increasing the amount of vitamin D serum levels, the serum levels of AMH have increased. © 2017 Informa UK Limited, trading as Taylor & Francis Group.

Item Type: Article
Additional Information: cited By 1
Uncontrolled Keywords: 25 hydroxyvitamin D; Muellerian inhibiting factor; 25-hydroxyvitamin D; Muellerian inhibiting factor; vitamin D, abortion; adult; Article; clinical article; clinical evaluation; drug effect; female; female fertility; female infertility; genital system; human; human cell; hysterectomy; hysterosalpingography; infertility therapy; live birth; medical history; menstrual cycle; parity; pelvis; pregnancy; priority journal; ultrasound; vitamin blood level; vitamin supplementation; analogs and derivatives; blood; dietary supplement; female infertility; treatment outcome, Adult; Anti-Mullerian Hormone; Dietary Supplements; Female; Humans; Infertility, Female; Treatment Outcome; Vitamin D
Subjects: WQ Obstetrics
QV Pharmacology
Depositing User: eprints admin
Date Deposited: 31 Dec 2018 07:14
Last Modified: 31 Dec 2018 07:14
URI: http://eprints.iums.ac.ir/id/eprint/6035

Actions (login required)

View Item View Item