The Burden of Statin Therapy based on ACC/AHA and NCEP ATP-III Guidelines: An Iranian Survey of Non-Communicable Diseases Risk Factors

Asgari, S. and Abdi, H. and Hezaveh, A.M. and Moghisi, A. and Etemad, K. and Beni, H.R. and Khalili, D. (2018) The Burden of Statin Therapy based on ACC/AHA and NCEP ATP-III Guidelines: An Iranian Survey of Non-Communicable Diseases Risk Factors. Scientific Reports, 8 (1).

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Abstract

To compare the burden of statin therapy according to the Third Adult Treatment Panel (ATP-III) and the American College of Cardiology/American Heart Association (ACC/AHA) guidelines the Survey of Risk Factors of Non-Communicable Disease (SuRFNCD)-2011of Iran was used. A survey analysis associated with sex and age categorization was run. Of total 3496 persons (1322 men) aged 40-70 years, based on the ACC/AHA guidelines, about 46.5 were eligible to receive moderate- to high-intensity statin therapy. Based on the ATP-III guidelines, 17.0 were considered as needing statin drugs. Among adults aged <60 years, the proportion of those who were eligible for statin therapy was higher (38.3) according to the ACC/AHA guidelines compared to the ATP-III guidelines (15.2), a difference more prominent in adults aged �60 years (85.2 versus 25.0). Agreement between the two guidelines was low (kappa: 0.32). Compared to the ATP-III guidelines, the ACC/AHA guidelines increase the number of adults eligible for statin therapy in an Iraninan population from 2.5 million to 7.0 million people according to the 2011 census, specifically in those aged � 60 years, a finding in agreement with those of studies from different countries. © 2018 The Author(s).

Item Type: Article
Additional Information: cited By 0
Subjects: WB Practice of Medicine
QV Pharmacology
Depositing User: eprints admin
Date Deposited: 25 Dec 2018 14:15
Last Modified: 30 Jun 2019 07:19
URI: http://eprints.iums.ac.ir/id/eprint/6172

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