Methicillin-resistant staphylococcus epidermidis in Iran: A systematic review and meta-analysis

Razavi, S. and Dadashi, M. and Pormohammad, A. and Khoramrooz, S.S. and Mirzaii, M. and Gholipour, A. and Darban-Sarokhalil, D. (2018) Methicillin-resistant staphylococcus epidermidis in Iran: A systematic review and meta-analysis. Archives of Clinical Infectious Diseases, 13 (4).

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Objective: Methicillin-resistant Staphylococcus epidermidis (MRSE) remains one of the most prevalent drug-resistant bacteria causing health care infections. Limited data are available about how the frequency of MRSE changed in Iran over the past years. The current study aimed at determining the frequency of MRSE in different cities of Iran. Methods: Databases including Web of Sciences, Scopus, Embase, Medline, and Iranian databases were searched to find studies addressing the frequency of MRSE in Iran published from Mar 2006 to Jan 2016. The data were analyzed using comprehensive meta-analysis version 2.2 (Biostat). Of the 139 records identified in the databases, 15 studies met the inclusion criteria. Results: The analyses showed that the frequency of MRSE infections was 73.9 95% confidence interval (95% CI) 61.4-83.4 among culture-positive cases of S. epidermidis in different parts of Iran. The frequency of MRSE was higher in the studies conducted from 2011 to 2015, based on further stratified analyses. Conclusions: The regular surveillance on antimicrobial susceptibility pattern and formulation of definite antibiotic policy may control high rate of MRSE associated infections in Iran. Moreover, rapid and reliable diagnosis of MRSE isolates and regular screening of the personnel and surfaces of hospitals in terms of MRSE are indispensable. © 2018, Archives of Clinical Infectious Diseases.

Item Type: Article
Additional Information: cited By 0
Subjects: QV Pharmacology
Depositing User: eprints admin
Date Deposited: 24 Dec 2018 08:33
Last Modified: 02 Jul 2019 06:31

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