A novel method for the synthesis of spiroindoline-pyrazolo4',3':5,6] pyrido2,3-dpyrimidinetriones by alum as a reusable catalyst

Shirvan, S.A. and Ghahremanzadeh, R. and Moghaddam, M.M. and Bazgir, A. and Zarnani, A.H. and Akhondi, M.M. (2012) A novel method for the synthesis of spiroindoline-pyrazolo4',3':5,6] pyrido2,3-dpyrimidinetriones by alum as a reusable catalyst. Journal of Heterocyclic Chemistry, 49 (4). pp. 951-954.

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Abstract

Synthesis of spiroindoline-pyrazolo4',3':5,6]pyrido2,3-dpyrimidine trione derivatives by a cyclo-condensation reaction of indolin-2-ones, barbituric acids, and 1,3-diphenyl-1H-pyrazol-5-amines with the ionic liquid as an effective green reaction media and in the presence of Alum as a reusable catalyst was reported. Excellent yields of products, green media, use of a reusable catalyst, and short reaction time are the main advantages of this new method. © 2012 HeteroCorporation.

Item Type: Article
Additional Information: cited By 11
Uncontrolled Keywords: aluminum potassium sulfate; barbituric acid; indole derivative; ionic liquid; pyrazole derivative; pyrido2,3 dpyrimidine derivative; spiro compound; spiroindoline pyrazolo4',3':5,6]pyrido2,3 dpyrimidinetrione derivative; unclassified drug, article; catalyst; chemical structure; polymerization; quantum yield; reaction analysis; reaction time; synthesis
Subjects: QV Pharmacology
Divisions: School of Rehabilitation Sciences
Depositing User: parto mrs bakhtminoo
Date Deposited: 07 Jan 2019 05:01
Last Modified: 07 Jan 2019 05:01
URI: http://eprints.iums.ac.ir/id/eprint/9891

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