Association between psychosocial distress with cardio metabolic risk factors and liver enzymes in a nationally-representative sample of Iranian children and adolescents: The CASPIAN-III study

Qorbani, M. and Kelishadi, R. and Taheri, E. and Motlagh, M.E. and Arzaghi, S.M. and Ardalan, G. and Chinian, M. and Mahmoudarabi, M. and Rezapoor, A. and Asayesh, H. and Larijani, B. and Amini, M.R. and Heshmat, R. (2014) Association between psychosocial distress with cardio metabolic risk factors and liver enzymes in a nationally-representative sample of Iranian children and adolescents: The CASPIAN-III study. Journal of Diabetes and Metabolic Disorders, 13 (1). ISSN 22516581

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Abstract

Background: The present study was designed to evaluate association of psychosocial distress with cardio metabolic risk factors and liver enzymes in Iranian children and adolescents.Method: This nationwide study was conducted as the third survey of the school-based surveillance system that was conducted among 5593 school students, 10-18 years in Iran. High triglyceride (TG), high fasting blood sugar (FBS), high total cholesterol (TC), high low-density lipoprotein cholesterol (LDL-C), low high-density lipoprotein cholesterol (HDL-C), hypertension (HTN), generalized obesity and abdominal obesity were considered as cardio metabolic risk factors and alanine transaminase (ALT) and aspartate aminotransferase (AST) were considered as liver enzymes. Data were analyzed using multiple logistic regression (MLR) analysis.Result: Psychosocial distress was detected in2027 (71.2) of boys and 1759 (63.3) of girls. Among boys, the mean of LDL, AST and DBP were higher and the mean FBS and HDL were lowering those with psychiatric distress than their other counterparts. Girls with psychosocial distress had significantly higher mean of HDL and FBS than those without psychiatric distress. Psychosocial distress significantly increased the odds of high LDL (OR = 2.36, 95CI 1.53, 3.64), high FBS (OR = 1.23, 95CI 1.02, 1.49) and low HDL (OR = 1.65, 95CI 1.41, 1.95).Conclusion: Psychosocial distress in adolescents is associated with increased risk of some cardio metabolic risk factors. © 2014 Qorbani et al.; licensee BioMed Central Ltd.

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