Rastgou, F. and Shojaeifard, M. and Amin, A. and Ghaedian, T. and Firoozabadi, H. and Malek, H. and Yaghoobi, N. and Bitarafan-Rajabi, A. and Haghjoo, M. and Amouzadeh, H. and Barati, H. (2014) Assessment of left ventricular mechanical dyssynchrony by phase analysis of gated-SPECT myocardial perfusion imaging and tissue Doppler imaging: Comparison between QGS and ECTb software packages. Journal of Nuclear Cardiology, 21 (6). pp. 1062-1071. ISSN 10713581
|
Text
Assessment of left ventricular mechanical dyssynchrony by phase analysis of gated-SPECT myocardial perfusion imaging and tissue Doppler imaging Comparison between QGS and ECTb software packages.pdf Download (1MB) | Preview |
Abstract
Background: Recently, the phase analysis of gated single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) has become feasible via several software packages for the evaluation of left ventricular mechanical dyssynchrony. We compared two quantitative software packages, quantitative gated SPECT (QGS) and Emory cardiac toolbox (ECTb), with tissue Doppler imaging (TDI) as the conventional method for the evaluation of left ventricular mechanical dyssynchrony. Methods and Results: Thirty-one patients with severe heart failure (ejection fraction ≤35%) and regular heart rhythm, who referred for gated-SPECT MPI, were enrolled. TDI was performed within 3 days after MPI. Dyssynchrony parameters derived from gated-SPECT MPI were analyzed by QGS and ECTb and were compared with the Yu index and septal-lateral wall delay measured by TDI. QGS and ECTb showed a good correlation for assessment of phase histogram bandwidth (PHB) and phase standard deviation (PSD) (r = 0.664 and r = 0.731, P < .001, respectively). However, the mean value of PHB and PSD by ECTb was significantly higher than that of QGS. No significant correlation was found between ECTb and QGS and the Yu index. Nevertheless, PHB, PSD, and entropy derived from QGS revealed a significant (r = 0.424, r = 0.478, r = 0.543, respectively; P < .02) correlation with septal-lateral wall delay. Conclusion: Despite a good correlation between QGS and ECTb software packages, different normal cut-off values of PSD and PHB should be defined for each software package. There was only a modest correlation between phase analysis of gated-SPECT MPI and TDI data, especially in the population of heart failure patients with both narrow and wide QRS complex. © 2014, American Society of Nuclear Cardiology.
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 15 |
| Uncontrolled Keywords: | algorithm; comparative study; computer assisted diagnosis; computer program; diagnosis; elastography; evaluation study; female; heart left ventricle function; human; image enhancement; male; middle aged; myocardial perfusion imaging; procedures; reproducibility; sensitivity and specificity; single photon emission computer tomography, Algorithms; Elasticity Imaging Techniques; Female; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Male; Middle Aged; Myocardial Perfusion Imaging; Reproducibility of Results; Sensitivity and Specificity; Software; Tomography, Emission-Computed, Single-Photon; Ventricular Dysfunction, Left |
| Subjects: | WG Cardiovascular System |
| Depositing User: | Ms Roya Vesal Azad |
| Date Deposited: | 01 Oct 2019 07:44 |
| Last Modified: | 01 Oct 2019 07:44 |
| URI: | http://eprints.iums.ac.ir/id/eprint/11094 |
Actions (login required)
 |
View Item |
