Subcutaneous sterile water injection for labour pain: A randomised controlled trial

Bahasadri, S. and Ahmadi-Abhari, S. and Dehghani-Nik, M. and Habibi, G.R. (2006) Subcutaneous sterile water injection for labour pain: A randomised controlled trial. Australian and New Zealand Journal of Obstetrics and Gynaecology, 46 (2). pp. 102-106.

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Background: About 30 of women experience severe continuous low-back pain in labour, but limited options are available to reduce this pain especially in developing countries and remote areas. Aims: To evaluate the efficacy of subcutaneous sterile water injection in reduction of labour pain compared with placebo. Methods: One hundred (100) consecutive patients were enrolled in a double-blind randomised controlled trial. During the first stage of labour with planned normal vaginal delivery, the intervention group (n = 50) received 0.5 mL sterile water injected subcutaneously and the control group (n = 50) received normal saline as a placebo. Pain score was measured before and 10 and 45 min after the injection, using the faces rating scale. Main outcome measure: Low-back labour pain. Results: The two groups were not significantly different regarding maternal age and weight, gestational age, parity and gravidity and degree of effacement. The median pain score was equal in both groups prior to the injection. Pain severity was reduced in both groups after the injection. However, the median pain score in the sterile water group was significantly lower than the placebo group 10 min (P < 0.01), as well as 45 min, after theinjection (P < 0.01). Conclusions: Administering one subcutaneous injection of sterile water in a painful point of the lumbosacral area is effective in reducing low-back pain during labour. © 2006 The Authors Journal compilation © 2006 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

Item Type: Article
Additional Information: cited By 23
Uncontrolled Keywords: placebo; sodium chloride; water, absence of side effects; adult; article; body weight; clinical trial; controlled clinical trial; controlled study; disease severity; double blind procedure; drug dose regimen; drug efficacy; female; gestational age; human; labor pain; labor stage 1; low back pain; major clinical study; maternal age; obstetric analgesia; pain assessment; parity; pregnancy; priority journal; randomized controlled trial; rating scale; uterine cervix ripening; vaginal delivery, Adult; Analgesia, Obstetrical; Double-Blind Method; Female; Gestational Age; Humans; Injections, Subcutaneous; Labor Pain; Labor Stage, First; Lumbosacral Region; Pain Measurement; Pregnancy; Pregnancy Outcome; Probability; Risk Assessment; Severity of Illness Index; Sodium Chloride; Statistics, Nonparametric; Sterilization; Treatment Outcome; Water
Subjects: WP Gynecology
WQ Obstetrics
Depositing User: Librarian Farzaneh Dini
Date Deposited: 08 Apr 2020 06:13
Last Modified: 08 Apr 2020 06:13

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