Prevalence and predictors of electrical storm in patients with implantable cardioverter-defibrillator

Arya, A. and Haghjoo, M. and Dehghani, M.R. and Fazelifar, A.F. and Nikoo, M.-H. and Bagherzadeh, A. and Sadr-Ameli, M.A. (2006) Prevalence and predictors of electrical storm in patients with implantable cardioverter-defibrillator. American Journal of Cardiology, 97 (3). pp. 389-392.

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Identifying predictors of electrical storm in patients with implantable cardioverter-defibrillators (ICDs) could help identify those at risk and reduce the incidence of this emergency situation, which has a detrimental effect on mortality and morbidity in patients with ICDs. This retrospective study sought to determine the prevalence and predictors of electrical storm in patients with ICDs. One hundred sixty-two patients (126 men; mean age 58 ± 13 years) who received ICDs from January 2001 to January 2005 were included in the study. Clinical, electrocardiographic, and ICD stored data and electrograms were collected and analyzed. Twenty-two patients (14) developed electrical storm during a mean follow-up of 14.3 ± 10 months. Using Cox multiple regression analysis, it was found that an ejection fraction <25 (p = 0.007), QRS width �120 ms (p = 0.002), and a lack of adjunctive angiotensin- converting enzyme inhibitor and β-blocker therapy (both p <0.001) were correlated with a greater probability of electrical storm. Adjunctive amiodarone and digoxin therapy, indication of ICD implantation, and age were not correlated with the occurrence of electrical storm during follow-up (all p = NS). In conclusion, electrical storm is not uncommon in patients with ICDs. Optimum medical therapy with β blockers and angiotensin-converting enzyme inhibitors could reduce the occurrence of electrical storm, and this especially should be considered in those at greater risk for this complication (i.e., those with left ventricular ejection fractions <25 and QRS widths �120 ms). © 2006 Elsevier Inc. All rights reserved.

Item Type: Article
Additional Information: cited By 67
Uncontrolled Keywords: amiodarone; beta adrenergic receptor blocking agent; digoxin; dipeptidyl carboxypeptidase inhibitor, adult; aged; article; controlled study; defibrillator; electrical storm; electrocardiography; electrography; female; follow up; heart arrhythmia; heart ejection fraction; human; major clinical study; male; prevalence; priority journal; proportional hazards model; QRS complex, Adult; Aged; Arrhythmia; Defibrillators, Implantable; Female; Heart Diseases; Humans; Iran; Male; Middle Aged; Prevalence; Retrospective Studies; Risk
Subjects: WG Cardiovascular System
Depositing User: Librarian Farzaneh Dini
Date Deposited: 08 Apr 2020 07:02
Last Modified: 08 Apr 2020 07:02

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