Correlation between results of head-up tilt test and clinical features in patients with syncope or presyncope

Emkanjoo, Z. and Alizadeh, A. and Alasti, M. and Fadaie, A.A. and Haghjoo, M. and Fazelifar, A.F. and Sadr-Ameli, M.A. (2007) Correlation between results of head-up tilt test and clinical features in patients with syncope or presyncope. Journal of Electrocardiology, 40 (2). pp. 200-202.


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Background: Head-up tilt test (HUTT) is a well-established diagnostic tool in patients with suspected vasovagal syncope. Identification of factors that predict a positive HUTT result could simplify diagnostic steps. The aim of this study was to assess the correlation between clinical characteristics of patients with suspected neurocardiogenic syncope or presyncope and results of HUTT. Materials and Methods: The study group consisted of 90 patients (55 men, 35 women; mean age, 43.2 ± 17 years) with a history of syncope or presyncope. Cardiological and neurologic test findings were normal in every patient. The patients were tilted to a 70° position for 45 minutes. If the first phase produced a negative response, the patients received 400 μg of sublingual nitroglycerin for the second phase and continued to be tilted for an additional 15 minutes. Results: Sixty-four patients had a positive HUTT result, characterized by a vasodepressive response in 26 patients, mixed response in 24 patients, and cardioinhibitory response in 14 patients. In logistic regression analysis, the presence of prodromal symptoms was a predictor of a positive HUTT result (P = .002). Conclusion: We showed that the prognostic performance of clinical features, including the time interval between the last episode and HUTT, the number of syncope or presyncope episodes, age, and sex, was not ideal. The presence of prodromal symptoms might be more likely to predict a positive response during HUTT. © 2007 Elsevier Inc. All rights reserved.

Item Type: Article
Additional Information: cited By 7
Uncontrolled Keywords: glyceryl trinitrate, adult; age distribution; article; cardiovascular response; clinical feature; controlled study; correlation analysis; diagnostic test; female; head tilting; human; logistic regression analysis; major clinical study; male; neurologic examination; presyncope; priority journal; prognosis; sex difference; syncope, Adult; Electrocardiography; Female; Humans; Male; Prognosis; Reproducibility of Results; Sensitivity and Specificity; Syncope, Vasovagal; Tilt-Table Test
Subjects: WG Cardiovascular System
Divisions: School of Rehabilitation Sciences
Depositing User: parto mrs bakhtminoo
Date Deposited: 26 Feb 2019 11:13
Last Modified: 26 Feb 2019 11:13

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