Global estimate of Neisseria meningitidis serogroups proportion in invasive meningococcal disease: A systematic review and meta-analysis

Purmohamad, A. and Abasi, E. and Azimi, T. and Hosseini, S. and Safari, H. and Nasiri, M.J. and Imani Fooladi, A.A. (2019) Global estimate of Neisseria meningitidis serogroups proportion in invasive meningococcal disease: A systematic review and meta-analysis. Microbial Pathogenesis, 134.

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Abstract

Using the PRISMA guideline, 102 studies were included in this study. The highest and the lowest proportion of N. meningitidis serogroups in invasive meningococcal disease (IMD) was for NmB with 48.5 (95 CI: 45�52) and NmX with 0.7 (95 CI: 0.3�1.7). Among the WHO regional offices, serogroup NmW with 57.5 (95 CI: 35�77.5) in Eastern Mediterranean, and NmZ with 0.1 (95 CI: 0�0.9) in America had the highest and the lowest proportion of N. meningitidis serogroups in IMD. NmC with 9.7 (95 CI: 5.6�16.2) and NmB with 9.5 (95 CI: 0.2�3.8) had the highest proportion in 1�4 and <1 year age groups, respectively. Our analysis showed that NmB had the highest proportion of N. meningitidis serogroups in IMD worldwide. However, proportion of N. meningitidis serogroups in IMD varied noticeably across countries and age groups. Therefore, establishing appropriate control guidelines depending on the geographical regions and age groups is essential for prevention of IMD. © 2019

Item Type: Article
Additional Information: cited By 0
Subjects: WC Communicable Diseases
WL Nervous System
Depositing User: eprints admin
Date Deposited: 23 Sep 2020 09:12
Last Modified: 23 Sep 2020 09:12
URI: http://eprints.iums.ac.ir/id/eprint/13282

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