Engineering the niche for hair regeneration � A critical review

Nilforoushzadeh, M.A. and Zare, M. and Zarrintaj, P. and Alizadeh, E. and Taghiabadi, E. and Heidari-Kharaji, M. and Amirkhani, M.A. and Saeb, M.R. and Mozafari, M. (2019) Engineering the niche for hair regeneration � A critical review. Nanomedicine: Nanotechnology, Biology, and Medicine, 15 (1). pp. 70-85.

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Recent progress in hair follicle regeneration and alopecia treatment necessitates revisiting the concepts and approaches. In this sense, there is a need for shedding light on the clinical and surgical therapies benefitting from nanobiomedicine. From this perspective, this review attempts to recognize requirements upon which new hair therapies are grounded; to underline shortcomings and opportunities associated with recent advanced strategies for hair regeneration; and most critically to look over hair regeneration from nanomaterials and pluripotent stem cell standpoint. It is noteworthy that nanotechnology is able to illuminate a novel path for reprogramming cells and controlled differentiation to achieve the desired performance. Undoubtedly, this strategy needs further advancement and a lot of critical questions have yet to be answered. Herein, we introduce the salient features, the hurdles that must be overcome, the hopes, and practical constraints to engineer stem cell niches for hair follicle regeneration. © 2018 Elsevier Inc.

Item Type: Article
Additional Information: cited By 3
Subjects: WR Dermatology
Depositing User: eprints admin
Date Deposited: 11 Nov 2020 09:51
Last Modified: 11 Nov 2020 09:51

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