Electrically conductive nanomaterials for cardiac tissue engineering

Ashtari, K. and Nazari, H. and Ko, H. and Tebon, P. and Akhshik, M. and Akbari, M. and Alhosseini, S.N. and Mozafari, M. and Mehravi, B. and Soleimani, M. and Ardehali, R. and Ebrahimi Warkiani, M. and Ahadian, S. and Khademhosseini, A. (2019) Electrically conductive nanomaterials for cardiac tissue engineering. Advanced Drug Delivery Reviews.

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Patient deaths resulting from cardiovascular diseases are increasing across the globe, posing the greatest risk to patients in developed countries. Myocardial infarction, as a result of inadequate blood flow to the myocardium, results in irreversible loss of cardiomyocytes which can lead to heart failure. A sequela of myocardial infarction is scar formation that can alter the normal myocardial architecture and result in arrhythmias. Over the past decade, a myriad of tissue engineering approaches has been developed to fabricate engineered scaffolds for repairing cardiac tissue. This paper highlights the recent application of electrically conductive nanomaterials (carbon and gold-based nanomaterials, and electroactive polymers) to the development of scaffolds for cardiac tissue engineering. Moreover, this work summarizes the effects of these nanomaterials on cardiac cell behavior such as proliferation and migration, as well as cardiomyogenic differentiation in stem cells. © 2019 Elsevier B.V.

Item Type: Article
Additional Information: cited By 0
Subjects: QS Human Anatomy
QT Physiology
Depositing User: eprints admin
Date Deposited: 11 Nov 2020 08:37
Last Modified: 11 Nov 2020 08:37
URI: http://eprints.iums.ac.ir/id/eprint/14390

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