Comparison of effects of three diets containing "fish oil", Iranian fat consumption pattern, and standard diet on serum glucose and insulin sensitivity in wistar rat

Mohammad Shirazi, M. and Taleban, F.A. and Sabet Kassaii, M. and Abadi, A. and Vafa, M.R. (2010) Comparison of effects of three diets containing "fish oil", Iranian fat consumption pattern, and standard diet on serum glucose and insulin sensitivity in wistar rat. Iranian Journal of Epidemiology, 6 (2). pp. 39-47.

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Abstract

Methods: Thirty female Wistar rats were randomly allocated to three dietary groups: a standard diet (containing soy bean-oil), diet containing fish oil and diet containing mixed oil which was designed based on Iranian population fatty acid intake. Dams in each group were fed one of the diets during pregnancy and lactation and the pups were also weaned onto the same diet. Fasting serum glucose (Photometry) and insulin (ELISA) in pups were assessed and insulin sensitivity calculated on puberty. Results: Fasting serum insulin in fish oil-fed group was significantly less than two other groups (P=0.018) and insulin sensitivity in fish oil-fed rats was significantly more than two other groups (P=0.002). Conclusions: It seems a diet containing fish oil (rich in long chain omega-3 fatty acids) causes more insulin sensitivity comparing to diet containing soy bean oil (rich in omega-6 fatty acids) and diet with Iranian population fatty acid intake pattern (rich in saturated fatty acids).

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: fish oil, animal experiment; article; comparative study; controlled study; enzyme linked immunosorbent assay; fat intake; female; glucose blood level; insulin sensitivity; lactation; nonhuman; photometry; pregnancy; rat; soybean
Subjects: WK Endocrine System
Depositing User: s shekarchi shekarchi
Date Deposited: 04 Oct 2021 09:41
Last Modified: 04 Oct 2021 09:41
URI: http://eprints.iums.ac.ir/id/eprint/21054

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