A combination of 670 nm and 810 nm diode lasers for wound healing acceleration in diabetic rats

Jahangiri Noudeh, Y. and Shabani, M. and Vatankhah, N. and Hashemian, S.J. and Akbari, K. (2010) A combination of 670 nm and 810 nm diode lasers for wound healing acceleration in diabetic rats. Photomedicine and Laser Surgery, 28 (5). pp. 621-627.

Full text not available from this repository.
Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....


Objectives: To study the effects of the combination of 670 nm and 810 nm diode lasers on diabetic wound healing parameters in rats. Background: An alternative to traditional treatment modalities for diabetic ulcers is low-level laser therapy (LLLT). A number of published studies demonstrate the beneficial effects of LLLT, although several other studies also exist which indicate results to the contrary. Methods: Four groups were present in our study: Diabetic-laser (n = 5), Diabetic-control (n = 4), Nondiabetic-laser (n = 5) and Nondiabetic-control (n = 5) groups. Two intervention (laser) groups underwent low level laser therapy using 670 nm diode laser (500 mW, 10 J, 48 s) in the wound context, and 810 nm diode laser (250 mW, 12 J, 50 s) to the wound margins. The wound area was measured using computer software after digital microscopic photography on days 0, 3, 6, 9, 12, 15, 20, and 24. Results: There were no statistically significant differences between the diabetic and non-diabetic groups in the wound area, percentage of open wound area, and wound healing rate throughout the repeated measurements of the study. After seven days of low level laser therapy in the non-diabetic group, urine excretion was significantly increased in comparison with the control group. Conclusion: Overall, our study showed results of measured wound healing parameters that were not significantly different in the LLLT group compared with the control group. The urine volume increase in non-diabetic rats after LLLT was an incidental observation that warrants future study. © Copyright 2010, Mary Ann Liebert, Inc. 2010.

Item Type: Article
Additional Information: cited By 21
Uncontrolled Keywords: Beneficial effects; Control groups; Diabetic rats; Diabetic ulcers; Diode lasers; Four-group; Low level laser therapy; Microscopic photography; Repeated measurements; Statistically significant difference; Treatment modality; Urine excretion; Wound healing, Body fluids; Diodes; Laser tissue interaction; Rats; Semiconductor lasers, Laser surgery, streptozocin, animal; article; comparative study; confidence interval; diode laser; disease model; experimental diabetes mellitus; immunohistochemistry; injury; low level laser therapy; male; methodology; microphotography; multivariate analysis; pathology; physiology; radiation dose; randomization; rat; reference value; Wistar rat; wound healing, Animals; Confidence Intervals; Diabetes Mellitus, Experimental; Disease Models, Animal; Immunohistochemistry; Laser Therapy, Low-Level; Lasers, Semiconductor; Male; Multivariate Analysis; Photomicrography; Radiation Dosage; Random Allocation; Rats; Rats, Wistar; Reference Values; Streptozocin; Wound Healing; Wounds and Injuries
Subjects: WK Endocrine System
QU Biochemistry. Cell Biology and Genetics
Depositing User: s shekarchi shekarchi
Date Deposited: 03 Oct 2021 05:05
Last Modified: 03 Oct 2021 05:05
URI: http://eprints.iums.ac.ir/id/eprint/21135

Actions (login required)

View Item View Item