Incidence and risk factors of transplant renal artery stenosis in living unrelated donor renal transplantation

Kamali, K. and Abbasi, M.A. and Behzadi, A.H. and Mortazavi, A. and Bastani, B. (2010) Incidence and risk factors of transplant renal artery stenosis in living unrelated donor renal transplantation. Journal of Renal Care, 36 (3). pp. 149-152.

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Background: This study was designed to evaluate the incidence and risk factors of transplant renal artery stenosis (TRAS) among living donor unrelated kidney recipients. Patients and methods: Three hundred and sixty kidney consecutive transplant recipients were included in this retrospective cohort study. Informed written consent was obtained, only TRAS occurring three months after transplantation were considered. After five-year follow up, TRAS was established in 6.6 (24 patients) of patients. Results: Mean ± SD age of recipients was 39.8 ± 14.9 years old (range 16-77). Upon multivariate analysis recipient age >50 (RR = 2.9, CI 95: 1.33-2.93, p = 0.008), recipient BMI >30 (kg/m2) (RR: 7.97, CI 95: 3.44-18.46, p < 0.001), retransplantation (RR = 4.88, CI 95: 2.21-10.77, p < 0.001), cytomegalovirus (CMV) infection and delayed graft function (DGF) (RR: 4.29, CI 95: 3.12-13.79, p = 0.01) appeared to be independently associated with TRAS. Positive CMV-antibody was more frequent in recipients with TRAS (95.83 vs. 70.8, p = 0.04) but all of them were HCV-antibody negative. Other variables as discussed were similar between two groups. Conclusion: High recipient age, BMI > 30, hyper trigelyceridaemia, previous transplantation, CMV infection and DGF are shown to be risk factors for TRAS. © 2010 European Dialysis and Transplant Nurses Association/European Renal Care Association.

Item Type: Article
Additional Information: cited By 17
Uncontrolled Keywords: adolescent; adult; aged; article; cytomegalovirus infection; delayed graft function; female; human; incidence; Iran; kidney artery stenosis; kidney transplantation; living donor; male; middle aged; multivariate analysis; retrospective study; risk factor, Adolescent; Adult; Aged; Cytomegalovirus Infections; Delayed Graft Function; Female; Humans; Incidence; Iran; Kidney Transplantation; Living Donors; Male; Middle Aged; Multivariate Analysis; Renal Artery Obstruction; Retrospective Studies; Risk Factors
Subjects: WJ Urogenital System
Depositing User: s shekarchi shekarchi
Date Deposited: 03 Oct 2021 05:52
Last Modified: 03 Oct 2021 05:52

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