Poormoghim, H. and Poorkarim, M.A. and Lakeh, M.M. and Heshmati, B.N. and Almasi, S. and Hakim, M. (2010) Preliminary study of cardiovascular manifestations and cardiac severity scale in 58 patients with systemic sclerosis in Iran using the Medsger scale. Journal of Tehran University Heart Center, 5 (1). pp. 14-18.
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Abstract
Background: Cardiac involvement in systemic sclerosis (SSc) is more prevalent than previously thought. In this study, the frequency and severity of cardiovascular involvement were assessed in SSc patients referred to Firouzgar Hospital. Methods: Fifty-eight patients with SSc, selected from the data bank of SSc patients, were reviewed for the frequency and severity of 8 organ involvements in this case series. The preliminary severity scale, published by international SSc study groups, was employed for the determination of the severity grade in the cardiovascular system. In the cardiac scoring scale, grade 0 represents normal heart (no cardiac involvement), grade 1 denotes mild involvement electrocardiography (ECG) conduction defect and a left ventricular ejection fraction (LVEF) of 45-49%), grade 2 signifies moderate involvement (arrhythmia, LVEF = 40-44%), grade 3 indicates severe involvement (LVEF <40%), and grade 4 stands for end stage (congestive heart failure and arrhythmia requiring treatment). Results: In this study, 24 (41.4%) patients were in the diffuse cutaneous (dcSSc) subset. The female to male ratio was 10.5:1, and the mean duration from symptom onset to diagnosis was 7.35 years for the dcSSc subset and 8.41 years for the limited cutaneous (lcSSc) subset of disease, there being no significant difference. Cardiac involvement in this series was seen in 13 (22.4%) cases; and there was no significant difference in terms of frequency and severity between the two disease subgroups (p value = 0.96 and p value = 0.46 respectively). Conclusion: Our findings showed that the cardiac involvement in this series was infrequent and that there was no significant difference in the severity of cardiovascular involvement between the two subtypes of SSc in the late stage of the disease.
| Item Type: | Article |
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| Additional Information: | cited By 4 |
| Uncontrolled Keywords: | adult; article; cardiomegaly; cardiovascular disease; cardiovascular system examination; case study; clinical feature; complete heart block; congestive cardiomyopathy; data base; disease duration; disease severity; echocardiography; electrocardiography; female; heart function; heart left anterior bundle branch block; heart left bundle branch block; heart left ventricle ejection fraction; heart muscle conduction disturbance; heart ventricle arrhythmia; hospital readmission; human; Iran; major clinical study; male; medical record review; Medsger Scale; patient assessment; pericardial effusion; Q wave; rating scale; scoring system; sex ratio; systemic sclerosis; thorax radiography |
| Subjects: | WG Cardiovascular System WR Dermatology WS Pediatrics |
| Depositing User: | s shekarchi shekarchi |
| Date Deposited: | 08 Dec 2020 06:50 |
| Last Modified: | 08 Dec 2020 06:50 |
| URI: | http://eprints.iums.ac.ir/id/eprint/21358 |
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