Fallahian, F. and Alavian, S.M. and Fallahian, V. and Zamani, F. (2010) Impact of immunosuppression and chemotherapy on reactivation of viral hepatitis. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 21 (4). pp. 621-627.
Full text not available from this repository.Abstract
Chemotherapy drugs, biological medications that are used to treat cancer, may cause hepatic side effects. Patients with pre-existing viral hepatitis may be more susceptible to exacerbation of their underlying liver disease, and risk of drug-induced hepatotoxicity. We conducted a search on immunosuppression, and its impact on reactivation of viral hepatitis, using the electro-nic medical databases. Before starting chemotherapy, it is recommended to record the past history of liver disease and check for hepatitis B virus (HBV) and hepatitis C virus (HCV) serology. In immunosuppressed patients, radiation toxicity, graft versus host disease, hepatic veno-occlusive disease, acalculous cholecystitis, tumor infiltration, ischemia, other viruses such as CMV and her-pes virus, and systemic infection should also be considered. Transplant recipients with serologic evidence of previous infection with hepatitis B or C, or those who receive organs from a seropositive donor, should have viral load levels monitored before and after transplantation and, may also require treatment. We believe that there is a role for prophylactic use of antiviral treatment in patients at risk for HBV reactivation.
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 6 |
| Uncontrolled Keywords: | antivirus agent; hepatitis B surface antigen; lamivudine, blood; hepatitis A; hepatitis B; Hepatitis B virus; hepatitis C; Hepatitis C virus; Hepatitis delta virus; human; immunology; immunosuppressive treatment; physiology; recurrent disease; review; virus activation, Antiviral Agents; Hepacivirus; Hepatitis A; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis C; Hepatitis Delta Virus; Humans; Immunosuppression; Lamivudine; Recurrence; Virus Activation |
| Subjects: | WC Communicable Diseases WI Digestive System |
| Depositing User: | s shekarchi shekarchi |
| Date Deposited: | 13 Dec 2020 06:13 |
| Last Modified: | 17 Oct 2021 06:32 |
| URI: | http://eprints.iums.ac.ir/id/eprint/21417 |
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