Can prodromal symptoms predict recurrence of vasovagal syncope?

Fazelifar, A.F. and Basiri, H.A. and Tolooie, A. and Haghjoo, M. and Barakpour, H. and Emkanjoo, Z. and Abkenar, H.B. and Zeighami, M. and Asgari, F. and Sadr-Ameli, M.A. (2008) Can prodromal symptoms predict recurrence of vasovagal syncope? Cardiology Journal, 15 (5). pp. 446-450.

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Background: Vasovagal syncope (VVS) is a common symptom with empirical therapy and high recurrence rate. Our goal was to determine whether the pattern of presyncopal prodromal symptoms can predict the recurrence probability of vasovagal syncope. Methods: Seventy-nine consecutive patients (male/female: 53/26) with history of VVS and positive tilt table test (TTT) were enrolled in the study and completed the follow-up time for one year. They all had normal electrocardiograms and cardiac echocardiography without underlying disease. All of them were evaluated meticulously for prodromal symptoms (diaphoresis, nausea, palpitation and blurred vision) and frequency of syncopal spells in their past medical history. They received metoprolol at maximum tolerated dose and were taught tilt training as an empirical therapy after TTT. Results: Fifty-four patients (68.4) reported at least one of the four main prodromal symptoms. Median syncopal ± presyncopal spells were 4 episodes. Forty-two patients (53.2) experienced recurrence of syncope or presyncope during the follow-up period. In recurrent symptomatic patients, diaphoresis had been more significantly reported in their past medical history (p = 0.018) and they had more syncopal spells before TTT (p = 0.001). Age, gender and type of TTT response did not have any effect on the recurrence of VVS. Conclusions: Patients with a history of diaphoresis as a prodromal symptom and more pre-tilt syncopal attacks experience more syncopal or presyncopal spells during follow-up. Copyright © 2008 Via Medica.

Item Type: Article
Additional Information: cited By 5
Uncontrolled Keywords: metoprolol, adult; aged; anamnesis; article; blurred vision; diaphoresis; drug megadose; female; follow up; head tilting; heart palpitation; human; major clinical study; male; maximum tolerated dose; nausea; predictor variable; recurrence risk; recurrent disease; symptom; syncope; tilt table test, Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Heart Rate; Humans; Male; Middle Aged; Nausea; Predictive Value of Tests; Prospective Studies; Recurrence; Sweating; Syncope, Vasovagal; Tilt-Table Test; Vision Disorders; Young Adult
Subjects: WG Cardiovascular System
Depositing User: Arezoo Ghasemi siani
Date Deposited: 26 Dec 2020 04:54
Last Modified: 26 Dec 2020 04:54

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