Burden of musculoskeletal disorders in Iran during 1990�2017: estimates from the Global Burden of Disease Study 2017

Shahrezaee, M. and Keshtkari, S. and Moradi-Lakeh, M. and Abbasifard, M. and Alipour, V. and Amini, S. and Arabloo, J. and Arzani, A. and Bakhshaei, M. and Barzegar, A. and Bijani, A. and Dianatinasab, M. and Eskandarieh, S. and Gheshlagh, R.G. and Ghashghaee, A. and Heidari-Soureshjani, R. and Irvani, S.S.N. and Lahimchi, A. and Maleki, S. and Manafi, N. and Manafi, A. and Mansournia, M.A. and Mohammadian-Hafshejani, A. and Bandpei, M.A.M. and Moradzadeh, R. and Naderi, M. and Pakshir, K. and Rafiei, A. and Rashedi, V. and Rezaei, N. and Rezapour, A. and Sahraian, M.A. and Shahabi, S. and Shamsi, M. and Soheili, A. and Soroush, A. and Zamani, M. and Mohajer, B. and Farzadfar, F. (2020) Burden of musculoskeletal disorders in Iran during 1990�2017: estimates from the Global Burden of Disease Study 2017. Archives of Osteoporosis, 15 (1).

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Summary: Musculoskeletal diseases (MSDs) are the leading cause of disability and facing them demands updated reports on their burden for efficient policymaking. We showed Iran had the highest female-to-male ratio and highest increase in the burden of musculoskeletal diseases, in the past three decades, worldwide. We further confirmed the role of population aging as the main cause. Purpose: MSDs comprise most of the top causes of years lived with disability (YLDs) worldwide and are rapidly increasing in lower- and middle-income countries. Here, we present disability and mortality due to MSDs in Iran at the national level from 1990 to 2017. Methods: We used Global Burden of Disease (GBD) 2017 Study data and standard methodology and presented the burden of MSDs in rates of years of life lost (YLLs), YLDs, and disability-adjusted life years (DALYs) during 1990�2017, for population aged � 5 years old. We further explored attributable risk factors and decomposed the changing trend in DALYs to assess underlying causes. Results: In Iran, MSDs were responsible for 1.82 million (95uncertainty interval UI 1.3�2.4) DALYs, in 2017. During the past 28 years, with 1.75% annualized percentage change (APC), Iran had the highest percentage increase in the all-ages MSD DALYs rate worldwide, while the age-standardized DALYs APC was negligible. Low back pain was the greatest contributor to DALYs and caused 4.5% of total DALYs. The female population is experiencing considerably higher burden of MSDs, with 115% and 48% higher all-ages YLLs and YLDs rates per 100,000, respectively (YLLs 28.7; YLDs 2629.1), than males (YLLs 13.2; YLDs 1766.1). However, due to wide UIs, difference was not significant. Only 17.6% of MSD YLDs are attributable to assessed risk factors. Conclusion: Despite that MSDs are rising as an important cause of disability in Iran, these conditions are not sufficiently addressed in health policies. There is urgent need for cross-sectoral engagement, especially addressing the MSDs in females. © 2020, International Osteoporosis Foundation and National Osteoporosis Foundation.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: adolescent; adult; Article; attributable risk; cerebrovascular accident; congenital malformation; depression; diabetes mellitus; disability; disability-adjusted life year; disease burden; female; global disease burden; gout; head; human; Iran; kidney function; low back pain; major clinical study; male; mortality; musculoskeletal disease; neck pain; priority journal; rheumatoid arthritis; risk factor; smoking
Subjects: WE Musculoskeletal System
Depositing User: eprints admin
Date Deposited: 04 Oct 2020 04:33
Last Modified: 04 Oct 2020 04:33
URI: http://eprints.iums.ac.ir/id/eprint/22981

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