Metabolic syndrome parameters in psychiatric disease: Current knowledge and future perspectives

Dehkohneh, S.G. and Azadi, S. and Rasouli-Azad, M. and Jalilian, J. and Ghasemineghad, A. and Vahed, N. and Razzaghi, F. and Jafari, L. and Abbaszadeh-Mashkani, S. (2020) Metabolic syndrome parameters in psychiatric disease: Current knowledge and future perspectives. International Journal of Pharmaceutical Research, 12 (3). pp. 1039-1061.

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Psychiatric diseases are a significant source of disability worldwide. Psychiatric disorders like schizophrenia, anxiety, mood disorders, major depressive disorder, obsessive-compulsive disorder, attention deficit disorder with hyperactivity, autism spectrum disorder, tourette syndrome, bipolar disorder, anxiety disorder, sleep disorder, post-traumatic stress disorder, personality disorders, phobia, eating disorders, sexual disorder, and cognitive disorder affect a sizeable proportion of the human population and severely compromise quality of life. Thus, measures to prevent the manifestation, and treatments to ameliorate the signs, of these disturbance are in high demand. The relationship between severe psychiatric illnesses and the metabolic disturbances is emerging as a public health question of importance to both primary care practitioners and mental health. Although several evidence have demonstrated a link between oxidative stress, glycemic control, inflammation, and lipid profiles with psychiatric disorders. Another critical aspect that needs much attention and effort is our understanding of the association between metabolic syndrome parameters and severe psychiatric illnesses. This review includes relevant articles published between 1990 and 2019. The aim of this review article is to examines the current knowledge and future perspectives related to the role of metabolic disorder (e.g., oxidative stress, glycemic control, inflammation, and lipid profiles) in patients with psychiatric disorder. © 2020, Advanced Scientific Research. All rights reserved.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: high density lipoprotein cholesterol; nitric oxide; reactive oxygen metabolite; serotonin uptake inhibitor; triacylglycerol, anorexia nervosa; anxiety disorder; attention deficit disorder; autism; automutilation; behavioral addiction; binge eating disorder; bipolar disorder; cognitive defect; coronary artery disease; degenerative disease; depression; diabetes mellitus; disorders of carbohydrate metabolism; Gilles de la Tourette syndrome; human; insulin resistance; major depression; mental disease; metabolic disorder; metabolic syndrome X; mood disorder; nerve degeneration; nervous system inflammation; neurosis; non insulin dependent diabetes mellitus; obesity; obsessive compulsive disorder; pathological gambling; personality disorder; Positive and Negative Syndrome Scale; posttraumatic stress disorder; prevalence; psychiatrist; psychosis; Review; schizophrenia; sexual dysfunction; sleep disordered breathing; social phobia; somatoform disorder; thyroid disease; tuberous sclerosis; vomiting
Subjects: WL Nervous System
Depositing User: eprints admin
Date Deposited: 20 Sep 2020 07:05
Last Modified: 20 Sep 2020 07:05

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