Prevalence of meningitis among hospitalized neonates with urinary tract infection

Saboute, M. and Kashaki, M. and Yavar, R. and Bordbar, A. and Khalessi, N. and Allahqoli, L. (2020) Prevalence of meningitis among hospitalized neonates with urinary tract infection. Iranian Journal of Neonatology, 11 (2). pp. 66-71.


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Background: Bacteremia is relatively common in children with urinary tract infection (UTI). The aim of the present study was to determine the frequency of bacterial meningitis among neonates with laboratory-confirmed UTI. Methods: This retrospective cross-sectional study was performed on 163 hospitalized neonates in Ali Asghar and Shahid Akbarabadi hospitals affiliated to Iran University of Medical Sciences in Tehran, Iran. The demographic and clinical data of hospitalized neonates due to UTI during the recent 6 years (2010-2016) who were aged < 28 days and had cerebrospinal fluid (CSF) culture via lumbar puncture were extracted from medical records and recorded in some checklists. Results: A total of 163 neonates with laboratory-confirmed UTI with the mean age of 18.25±5.41 days were included. In this study, 54 of the neonates were male. Out of all neonates, 23 (14.1) cases had positive blood culture. The positive CSF culture was observed in only two (1.2) neonates. Positive voiding cystourethrogram (VCUG) test was reported in 50 of the neonates with positive CSF culture (P=0.047). Although abnormal ultrasound findings related to the urinary tract in positive CSF neonates were higher by approximately twofold, compared to those reported for negative CSF neonates, this difference was not statistically significant (50 and 24.2, respectively; P=0.432). Conclusion: The frequency of the concurrent occurrence of UTI and meningitis in our neonates was 1.2. Out of all indicators associated with meningitis occurrence, positive VCUG may be a risk factor. Further prospective studies are needed to approve these results. © 2020 Mashhad University of Medical Sciences. All rights reserved.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: antibiotic agent; C reactive protein, Acinetobacter; Article; bacterial meningitis; blood culture; cerebrospinal fluid culture; cross-sectional study; echography; Enterobacter; Enterococcus; Escherichia coli; female; hospitalized child; human; Klebsiella; laboratory test; lumbar puncture; major clinical study; male; medical record; micturition; micturition cystourethrography; newborn; outcome assessment; prevalence; retrospective study; Staphylococcus haemolyticus; Staphylococcus saprophyticus; Streptococcus pneumoniae; Streptococcus viridians; urinary tract infection
Subjects: WJ Urogenital System
WS Pediatrics
Depositing User: eprints admin
Date Deposited: 20 Sep 2020 04:30
Last Modified: 20 Sep 2020 04:30

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