Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study

Nikpouraghdam, M. and Jalali Farahani, A. and Alishiri, G. and Heydari, S. and Ebrahimnia, M. and Samadinia, H. and Sepandi, M. and Jafari, N.J. and Izadi, M. and Qazvini, A. and Dorostkar, R. and Tat, M. and Shahriary, A. and Farnoosh, G. and Hosseini Zijoud, S.R. and Taghdir, M. and Alimohamadi, Y. and Abbaszadeh, S. and Gouvarchin Ghaleh, H.E. and Bagheri, M. (2020) Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study. Journal of Clinical Virology, 127.


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Background: An outbreak of COVID-19 in Iran has spread throughout the country. Identifying the epidemiological characteristics of this disease will help to make appropriate decisions and thus control the epidemic. The aim of this study was characterization of the epidemiological features of COVID-19 in Iran. Methods: In this retrospective study, data related to the epidemiological characteristics of COVID-19 patients admitted to Baqiyatallah Hospital in Tehran, Iran, from 19 February 2020 to 15 April 2020 have been analyzed and reported. Patient characteristics including age, gender and underlying diseases were investigated. Data were collected through patient records. Sex ratio, Case Fatality Rate (CFR) and daily trend of cases were also determined. A multiple logistic regression analysis was also performed to assess affecting factors on mortality. Results: From February 19, 2020 to April 15, 2020, 12870 patients referred to the hospital emergency department, of which 2968 were hospitalized with COVID-19 diagnosis. The majority of cases were in the age group of 50 to 60 years of old. The male-to-female ratio was 1.93:1. A total of 239 deaths occurred among all cases for an overall CFR of 1.85 based on the total number of patients (both outpatient and inpatient) and 8.06 among hospitalized patients. Out of all patients 10.89 had comorbidity. Diabetes, chronic respiratory diseases, hypertension, cardiovascular diseases, chronic Kidney diseases and cancer were the most common comorbidities with 3.81, 2.02, 1.99, 1.25, 0.60 and 0.57 , respectively. Male gender (OR=1.45, 95 CI: 1.08-1.96), older age (OR=1.05, 95 CI: 1.04-1.06) and having underlying diseases (OR=1.53, 95 CI: 1.04-2.24) were significantly associated with mortality. Conclusions: The results of this study showed that Male gender, older age and having comorbidities were significantly associated with the risk of death among COVID-19 patients. It is important to pay special attention to male elderly patients with underlying diseases. © 2020 Elsevier B.V.

Item Type: Article
Additional Information: cited By 12
Uncontrolled Keywords: adolescent; adult; aged; Article; cardiovascular disease; case fatality rate; child; chronic kidney failure; chronic respiratory tract disease; comorbidity; coronavirus disease 2019; diabetes mellitus; female; hospital patient; human; hypertension; infant; Iran; major clinical study; male; malignant neoplasm; middle aged; mortality; newborn; priority journal; retrospective study; Severe acute respiratory syndrome coronavirus 2; sex ratio; very elderly; age; Betacoronavirus; Coronavirus infection; hospitalization; mortality; pandemic; preschool child; risk factor; sex factor; statistical model; virus pneumonia; young adult, Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Betacoronavirus; Child; Child, Preschool; Comorbidity; Coronavirus Infections; Female; Hospitalization; Humans; Infant; Infant, Newborn; Iran; Logistic Models; Male; Middle Aged; Pandemics; Pneumonia, Viral; Retrospective Studies; Risk Factors; Sex Factors; Young Adult
Subjects: WA Public Health
WC Communicable Diseases
Depositing User: eprints admin
Date Deposited: 19 Sep 2020 09:47
Last Modified: 19 Sep 2020 09:47
URI: http://eprints.iums.ac.ir/id/eprint/23429

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