Asbaghi, O. and Sadeghian, M. and Rahmani, S. and Mardani, M. and Khodadost, M. and Maleki, V. and Pirouzi, A. and Talebi, S. and Sadeghi, O. (2020) The effect of green coffee extract supplementation on anthropometric measures in adults: A comprehensive systematic review and dose-response meta-analysis of randomized clinical trials. Complementary Therapies in Medicine, 51.
Full text not available from this repository.Abstract
Background and aim: Two meta-analyses summarized data on the effects of green coffee extract (GCE) supplementation on anthropometric measures. However, the accuracy of those meta-analyses is uncertain due to several methodological limitations. Therefore, we aimed to conduct a comprehensive systematic review and dose-response meta-analysis to summarize all available evidence on the effects of GCE supplementation on anthropometric measures by considering the main limitations in the previous meta-analyses. Methods: We searched available online databases for relevant publications up to January 2020, using relevant keywords. All randomized clinical trials (RCTs) investigating the effects of GCE supplementation, compared with a control group, on anthropometric measures including body weight, body mass index (BMI), body fat percentage, waist circumference (WC) and waist-to-hip ratio (WHR) were included. Results: After identifying 1871 studies from our initial search, 15 RCTs with a total sample size of 897 participants were included in the systematic review and meta-analysis. We found a significant reducing effect of GCE supplementation on body weight (weighted mean difference (WMD): �1.23, 95 % CI: �1.64, �0.82 kg,P < 0.001), BMI (WMD: �0.48, 95 % CI: �0.78, �0.18 kg/m2, P = 0.001), and WC (WMD: �1.00, 95 % CI: �1.70, �0.29 cm, P = 0.006). No significant effect of GCE supplementation on body fat percentage and WHR was seen. In the dose-response analyses, there was no significant association between chlorogenic acid (CGA) dosage, as the main polyphenol in green coffee, and changes in anthropometric measures. Conclusion: We found that GCE supplementation had a beneficial effect on body weight, BMI and WC. It provides a cost-effective and safe alternative for the treatment of obesity. Additional well-designed studies are required to further confirm our findings. © 2020 Elsevier Ltd
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 1 |
| Uncontrolled Keywords: | chlorogenic acid; polyphenol, abdominal obesity; adverse outcome; anthropometry; body fat; body mass; clinical effectiveness; coffee; diet supplementation; human; meta analysis; randomized controlled trial (topic); Review; systematic review; therapy effect; treatment planning; waist circumference; waist hip ratio |
| Subjects: | WA Public Health WB Practice of Medicine |
| Depositing User: | eprints admin |
| Date Deposited: | 15 Sep 2020 06:13 |
| Last Modified: | 15 Sep 2020 06:13 |
| URI: | http://eprints.iums.ac.ir/id/eprint/23562 |
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