Chaichian, S. and Moazzami, B. and Sadoughi, F. and Haddad Kashani, H. and Zaroudi, M. and Asemi, Z. (2020) Functional activities of beta-glucans in the prevention or treatment of cervical cancer. Journal of Ovarian Research, 13 (1).
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Abstract
Cervical cancer is the fourth-ranked cancer in the world and is associated with a large number of deaths annually. Chemotherapy and radiotherapy are known as the common therapeutic approaches in the treatment of cervical cancer, but because of their side effects and toxicity, researchers are trying to discovery alternative therapies. Beta-glucans, a group of glucose polymers that are derived from the cell wall of fungi, bacteria, and etc. it has been showed that beta-glucans have some anti-cancer properties which due to their impacts on adaptive and innate immunity. Along to these impacts, these molecules could be used as drug carriers. In this regard, the application of beta-glucans is a promising therapeutic option for the cancer prevention and treatment especially for cervical cancer. Herein, we have summarized the therapeutic potential of beta-glucans alone or as adjuvant therapy in the treatment of cervical cancer. Moreover, we highlighted beta-glucans as drug carriers for preventive and therapeutic purposes. © 2020 The Author(s).
| Item Type: | Article |
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| Additional Information: | cited By 1 |
| Uncontrolled Keywords: | beta glucan; cytokine; drug carrier; monoclonal antibody; Wart virus vaccine, adaptive immunity; adjuvant therapy; antineoplastic activity; cancer adjuvant therapy; cancer chemotherapy; cancer growth; cancer immunotherapy; cancer prevention; cancer radiotherapy; cytokine release; drug efficacy; drug mechanism; human; immunomodulation; innate immunity; myeloid-derived suppressor cell; nonhuman; papillomavirus infection; priority journal; Review; tumor immunity; uterine cervix cancer |
| Subjects: | WB Practice of Medicine WP Gynecology QZ Pathology |
| Depositing User: | eprints admin |
| Date Deposited: | 08 Sep 2020 08:39 |
| Last Modified: | 08 Sep 2020 08:39 |
| URI: | http://eprints.iums.ac.ir/id/eprint/23886 |
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