Exosomal miRNAs: Novel players in viral infection

Nahand, J.S. and Mahjoubin-Tehran, M. and Moghoofei, M. and Pourhanifeh, M.H. and Mirzaei, H.R. and Asemi, Z. and Khatami, A. and Bokharaei-Salim, F. and Mirzaei, H. and Hamblin, M.R. (2020) Exosomal miRNAs: Novel players in viral infection. Epigenomics, 12 (4). pp. 353-370.

Full text not available from this repository.
Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....


Exosomes are secreted nanovesicles that are able to transfer their cargo (such as miRNAs) between cells. To determine to what extent exosomes and exosomal miRNAs are involved in the pathogenesis, progression and diagnosis of viral infections. The scientific literature (PubMed and Google Scholar) was searched from 1970 to 2019. The complex biogenesis of exosomes and miRNAs was reviewed. Exosomes contain both viral and host miRNAs that can be used as diagnostic biomarkers for viral diseases. Viral proteins can alter miRNAs, and conversely miRNAs can alter the host response to viral infections in a positive or negative manner. It is expected that exosomal miRNAs will be increasingly used for diagnosis, monitoring and even treatment of viral infections. © 2020 Future Medicine Ltd.

Item Type: Article
Additional Information: cited By 6
Uncontrolled Keywords: microRNA; RNA; viral protein, biogenesis; cell function; DNA virus infection; exosome; human; immune response; multivesicular body; nonhuman; priority journal; Review; RNA binding; RNA virus infection; surface property; virus infection
Subjects: WC Communicable Diseases
Depositing User: eprints admin
Date Deposited: 02 Sep 2020 08:33
Last Modified: 02 Sep 2020 08:33
URI: http://eprints.iums.ac.ir/id/eprint/24154

Actions (login required)

View Item View Item