Mohammadi, A.A. and Jazayeri, S. and Khosravi-Darani, K. and Solati, Z. and Mohammadpour, N. and Asemi, Z. and Adab, Z. and Djalali, M. and Tehrani-Doost, M. and Hosseini, M. and Eghtesadi, S. (2016) The effects of probiotics on mental health and hypothalamic�pituitary�adrenal axis: A randomized, double-blind, placebo-controlled trial in petrochemical workers. Nutritional Neuroscience, 19 (9). pp. 387-395.
Full text not available from this repository.Abstract
Objective: The aim of this study was to determine effects of probiotic yogurt and multispecies probiotic capsule supplementation on mental health and hypothalamicâ��pituitaryâ��adrenal axis in petrochemical workers. Methods: The present randomized double-blind, placebo-controlled trial was conducted on 70 petrochemical workers. Subjects were randomly divided into three groups to receive 100â� g/day probiotic yogurt + one placebo capsule (n = 25) or one probiotic capsule daily + 100â� g/day conventional yogurt (n = 25) or 100â� g/day conventional yogurt + one placebo capsule (n = 20) for 6 weeks. Mental health parameters including general health questionnaire (GHQ) and depression anxiety and stress scale (DASS) scores were measured. Fasting blood samples were obtained at the beginning and 6 weeks after the intervention to quantify hypothalamicâ��pituitaryâ��adrenal axis. Results: After 6 weeks of intervention, a significant improvement of GHQ was observed in the probiotic yogurt (18.0 ± 1.5 vs. 13.5 ± 1.9, P = 0.007) and in the probiotic capsule group (16.9 ± 1.8 vs. 9.8 ± 1.9, P = 0.001), as well as a significant improvement in DASS scores in the probiotic yogurt (23.3 ± 3.7 vs. 13.0 ± 3.7, P = 0.02) and the probiotic capsule group (18.9 ± 3.2 vs. 9.4 ± 4.0, P = 0.006). However, there was no significant improvement in the conventional yogurt group (P = 0.05 for GHQ and P = 0.08 for DASS). Discussion: The consumption of probiotic yogurt or a multispecies probiotic capsule had beneficial effects on mental health parameters in petrochemical workers. © 2016, © W. S. Maney & Son Ltd 2016.
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 36 |
| Depositing User: | eprints admin |
| Date Deposited: | 08 Jul 2018 04:06 |
| Last Modified: | 08 Jul 2018 04:06 |
| URI: | http://eprints.iums.ac.ir/id/eprint/3042 |
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