Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis

Nosrati, H. and Aramideh Khouy, R. and Nosrati, A. and Khodaei, M. and Banitalebi-Dehkordi, M. and Ashrafi-Dehkordi, K. and Sanami, S. and Alizadeh, Z. (2021) Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis. Journal of Nanobiotechnology, 19 (1).


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Skin is the body�s first barrier against external pathogens that maintains the homeostasis of the body. Any serious damage to the skin could have an impact on human health and quality of life. Tissue engineering aims to improve the quality of damaged tissue regeneration. One of the most effective treatments for skin tissue regeneration is to improve angiogenesis during the healing period. Over the last decade, there has been an impressive growth of new potential applications for nanobiomaterials in tissue engineering. Various approaches have been developed to improve the rate and quality of the healing process using angiogenic nanomaterials. In this review, we focused on molecular mechanisms and key factors in angiogenesis, the role of nanobiomaterials in angiogenesis, and scaffold-based tissue engineering approaches for accelerated wound healing based on improved angiogenesis.Figure not available: see fulltext. © 2021, The Author(s).

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: Scaffolds (biology); Tissue regeneration, Chronic wounds; Healing process; Molecular mechanism; Nanobiomaterials; Nanocomposite scaffolds; Quality of life; Scaffold based tissue engineering; Wound healing, Tissue
Subjects: QT Physiology
Depositing User: eprints admin
Date Deposited: 10 Mar 2021 04:17
Last Modified: 10 Mar 2021 04:17

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