Lymphadenectomy in endometrial cancer�achieving more with less?

Gitas, G. and Freytag, D. and Allahqoli, L. and Baum, S. and Rody, A. and Maass, N. and Dinas, K. and LaganÃ, A.S. and Moawad, G. and Sotiriadis, A. and Alkatout, I. (2021) Lymphadenectomy in endometrial cancerâ��achieving more with less? Minimally Invasive Therapy and Allied Technologies.

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The lymph node status of patients with endometrial cancer is known to be a crucial determinant for the prognosis of the disease. It also provides the indication for further adjuvant treatment. The staging of endometrial cancer by surgery has been a controversial issue for more than 30 years. The significant complication rate after lymphadenectomy and the development of minimally invasive surgery have led to the use of sentinel lymph node (SLN) mapping. In the present review, we present the development of surgical staging procedures in patients with endometrial cancer and summarize the recently expanding body of published literature on the subject. SLN mapping is a safe and accurate technique, especially when indocyanine green is used as a tracer. SLN mapping appears to reduce complication rates as well as costs without affecting the oncologic outcome. Large prospective studies are needed to establish the effects of SLN mapping on the outcome of disease, especially in high-risk patients with endometrial cancer. Furthermore, the need for additional systematic lymphadenectomy prior to adjuvant radio-chemotherapy in patients diagnosed with isolated lymph node metastasis during SLN biopsy must be investigated further. This might pave the way for a new surgical approach in patients with endometrial cancer. © 2020 Society of Medical Innovation and Technology.

Item Type: Article
Additional Information: cited By 0
Subjects: WP Gynecology
Depositing User: eprints admin
Date Deposited: 06 Apr 2021 07:56
Last Modified: 06 Apr 2021 07:56

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