Recent advances in ultrasound-triggered drug delivery through lipid-based nanomaterials

Ahmadi, A. and Hosseini-Nami, S. and Abed, Z. and Beik, J. and Aranda-Lara, L. and Samadian, H. and Morales-Avila, E. and Jaymand, M. and Shakeri-Zadeh, A. (2020) Recent advances in ultrasound-triggered drug delivery through lipid-based nanomaterials. Drug Discovery Today, 25 (12). pp. 2182-2200.

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The high prescribed dose of anticancer drugs and their resulting adverse effects on healthy tissue are significant drawbacks to conventional chemotherapy (CTP). Ideally, drugs should have the lowest possible degree of interaction with healthy cells, which would diminish any adverse effects. Therefore, an ideal scenario to bring about improvements in CTP is the use of technological strategies to ensure the efficient, specific, and selective transport and/or release of drugs to the target site. One practical and feasible solution to promote the efficiency of conventional CTP is the use of ultrasound (US). In this review, we highlight the potential role of US in combination with lipid-based carriers to achieve a targeted CTP strategy in engineered smart drug delivery systems. © 2020 Elsevier Ltd

Item Type: Article
Additional Information: cited By 2
Subjects: QV Pharmacology
Depositing User: eprints admin
Date Deposited: 16 May 2021 07:35
Last Modified: 16 May 2021 07:35

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