Contribution of nucleus raphe magnus to thermoregulation

Arami, M.K. and Komaki, A. and Gharibzadeh, S. (2020) Contribution of nucleus raphe magnus to thermoregulation. Physiology and Pharmacology (Iran), 24 (3). pp. 165-173.


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Thermoregulation is the maintenance of the core body temperature. The regulation of body temperature is one of the most important functions of the nervous system. Nucleus raphe magnus, as a central circuit coordinates the homeostatic response and maintains body temperature during environmental temperature challenges and adjusts body temperature during the inflammatory response and behavioral states and in response to decreasing energy homeostasis. Our aim in this review is the understanding of thermoregulation by raphe magnus in mammals. This review summarizes the basic concepts of thermoregulation and subsequently assesses the physiological responses to cold stress, including skin blood flow control, sweating, sympathetic-derived cutaneous vasoconstriction and peripheral thermoregulatory control in brown adipose tissue. © 2020, Iranian Society of Physiology and Pharmacology. All rights reserved.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: brown adipose tissue; cold stress; mammal; nonhuman; raphe magnus nucleus; review; skin blood flow; thermoregulation; vasoconstriction
Subjects: WL Nervous System
Depositing User: eprints admin
Date Deposited: 30 May 2021 04:16
Last Modified: 30 May 2021 04:16

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