Phthalate acid esters in pickled vegetables packaged in polyethylene terephthalate container: Occurrence, migration, and estrogenic activity-associated risk assessment

Cheshmazar, E. and Arfaeinia, L. and Vasseghian, Y. and Ramavandi, B. and Moradi, M. and Hashemi, S.E. and Asgari, E. and Arfaeinia, H. and Dragoi, E.-N. and Mousavi Khaneghah, A. (2021) Phthalate acid esters in pickled vegetables packaged in polyethylene terephthalate container: Occurrence, migration, and estrogenic activity-associated risk assessment. Journal of Food Composition and Analysis, 99.

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Abstract

Phthalate acid esters (PAEs) in plastic products such as plastic-based containers are not chemically bonded. The migration of these compounds from the wall of the plastic containers into the water and food packaged is a health concern. The current work investigates the aspects leading to PAEs migration from the wall of polyethylene terephthalate (PET) containers into pickled vegetables and their estrogenic�based risk evaluation. Six PAEs compounds with control priority (dimethyl phthalate, diethyl phthalate, di-n-butyl phthalate, butyl benzyl phthalate, bis (2-Ethylhexyl) phthalate, and di-n-octyl phthalate) were characterized and analyzed using 40 samples of pickles packaged in PET containers. It was found that the concentration of diethyl phthalate and di-n-butyl phthalate exceeded the EU limits (1.5 and 0.3 mg/kg, respectively). A positive and significant relation between PAEs concentration in pickles and storage temperature, storage time, and exposure to sunlight has been observed (P-value < 0.05). In contrast, a negative and significant relationship between pH and PAEs concentration has been detected (P-value < 0.05). The risk assessment of human daily intake indicated a diethyl phthalate safety factor lower than 1 (0.63 for adults and 0.39 for children), suggesting an increased health risk. Also, indexes of estrogenic activity associated-risk assessment were significantly high, indicating a high probability of adverse effects for human health. © 2021 Elsevier Inc.

Item Type: Article
Additional Information: cited By 0
Subjects: WA Public Health
WB Practice of Medicine
Depositing User: eprints admin
Date Deposited: 06 Dec 2021 09:51
Last Modified: 06 Dec 2021 09:51
URI: http://eprints.iums.ac.ir/id/eprint/39314

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