Agah, S. and Akbari, A. and Sadeghi, E. and Morvaridzadeh, M. and Basharat, Z. and Palmowski, A. and Heshmati, J. (2021) Resveratrol supplementation and acute pancreatitis: A comprehensive review. Biomedicine and Pharmacotherapy, 137.
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Resveratrol supplementation and acute pancreatitis A comprehensive review.pdf Download (2MB) |
Abstract
Resveratrol, a natural polyphenolic ingredient extracted from herbs, suppresses oxidative stress and inflammation. We performed a comprehensive review to find any evidence about the effects of Resveratrol on acute pancreatitis (AP). Resveratrol has been found to directly impact cytokine generation. As these factors play a crucial role in the pathophysiology of AP, resveratrol might attenuate AP and its complications. Mechanistically, resveratrol exerts its pharmacological effects through anti-inflammatory and antioxidant mechanisms via interaction with different signaling molecules and transcription factors. Indeed, resveratrol might prove to be an effective therapeutic component for AP treatment in the future. In this review, we shed light on potential most recent pathways through which resveratrol might impact the management and control of AP. © 2021
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 1 |
| Uncontrolled Keywords: | calcium; cytokine; mediator complex; pancreas enzyme; resveratrol; transcription factor, acute pancreatitis; antiinflammatory activity; antioxidant activity; calcium overload; drug effect; drug protein binding; gene expression; human; inflammation; intoxication; nonhuman; oxidative stress; pathophysiology; priority journal; Review; supplementation; tissue injury |
| Subjects: | QV Pharmacology |
| Depositing User: | eprints admin |
| Date Deposited: | 08 Jan 2022 05:52 |
| Last Modified: | 08 Jan 2022 05:52 |
| URI: | http://eprints.iums.ac.ir/id/eprint/39479 |
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