Risk factors prediction, clinical outcomes, and mortality in COVID-19 patients

Alizadehsani, R. and Alizadeh Sani, Z. and Behjati, M. and Roshanzamir, Z. and Hussain, S. and Abedini, N. and Hasanzadeh, F. and Khosravi, A. and Shoeibi, A. and Roshanzamir, M. and Moradnejad, P. and Nahavandi, S. and Khozeimeh, F. and Zare, A. and Panahiazar, M. and Acharya, U.R. and Islam, S.M.S. (2021) Risk factors prediction, clinical outcomes, and mortality in COVID-19 patients. Journal of Medical Virology, 93 (4). pp. 2307-2320.

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Preventing communicable diseases requires understanding the spread, epidemiology, clinical features, progression, and prognosis of the disease. Early identification of risk factors and clinical outcomes might help in identifying critically ill patients, providing appropriate treatment, and preventing mortality. We conducted a prospective study in patients with flu-like symptoms referred to the imaging department of a tertiary hospital in Iran between March 3, 2020, and April 8, 2020. Patients with COVID-19 were followed up after two months to check their health condition. The categorical data between groups were analyzed by Fisher's exact test and continuous data by Wilcoxon rank-sum test. Three hundred and nineteen patients (mean age 45.48 ± 18.50 years, 177 women) were enrolled. Fever, dyspnea, weakness, shivering, C-reactive protein, fatigue, dry cough, anorexia, anosmia, ageusia, dizziness, sweating, and age were the most important symptoms of COVID-19 infection. Traveling in the past 3 months, asthma, taking corticosteroids, liver disease, rheumatological disease, cough with sputum, eczema, conjunctivitis, tobacco use, and chest pain did not show any relationship with COVID-19. To the best of our knowledge, a number of factors associated with mortality due to COVID-19 have been investigated for the first time in this study. Our results might be helpful in early prediction and risk reduction of mortality in patients infected with COVID-19. © 2020 Wiley Periodicals LLC

Item Type: Article
Additional Information: cited By 6
Uncontrolled Keywords: C reactive protein; corticosteroid, adult; age; ageusia; anorexia; anosmia; Article; controlled study; coronavirus disease 2019; critically ill patient; dizziness; dry cough; dyspnea; fatigue; female; fever; flu like syndrome; follow up; human; Iran; major clinical study; male; mortality; prediction; prospective study; risk factor; risk reduction; shivering; sweating; tertiary care center; weakness; critical illness; diagnosis; disease exacerbation; epidemiology; isolation and purification; middle aged; pathology; therapy, Adult; COVID-19; Critical Illness; Disease Progression; Female; Humans; Iran; Male; Middle Aged; Prospective Studies; Risk Factors; SARS-CoV-2
Subjects: WA Public Health
WC Communicable Diseases
Depositing User: eprints admin
Date Deposited: 06 Nov 2022 08:22
Last Modified: 06 Nov 2022 08:22
URI: http://eprints.iums.ac.ir/id/eprint/39639

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