Dose response characteristics of a novel CCD camera-based electronic portal imaging device comparison with OCTAVIUS detector

Anvari, A. and Aghamiri, S.M.R. and Mahdavi, S.R. and Alaei, P. (2015) Dose response characteristics of a novel CCD camera-based electronic portal imaging device comparison with OCTAVIUS detector. Journal of Cancer Research and Therapeutics, 11 (4). pp. 765-769.

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Abstract

Aim: Dosimetric properties of a CCD camera-based Electronic Portal Imaging Device (EPID) for clinical dosimetric application have been evaluated. Characteristics obtained by EPID also compared with commercial 2D array of ion chambers. Materials and Methods: Portal images acquired in dosimetry mode then exported raw fluence or uncorrected images were investigated. Integration time of image acquisition mode has adjusted on 1 s per frame. Results: As saturation of camera of the EPID, dose response does not have linear behavior. The slight nonlinearity of the camera response can be corrected by a logarithmic expression. A fourth order polynomial regression model with coefficient of determination of 0.998 predicts a response to absolute dose values at less than 50 cGy. A field size dependent response of up to 7 (0.99-1.06) relative OCTAVIUS detector measurement was found. The EPID response can be fitted by a cubic regression for field size changes, yielded coefficient of determination of 0.999. Conclusions: These results indicate that the EPID is well suited for accurate dosimetric purposes, the major limitation currently being due to integration time and dead-time in frame acquisition. © 2015 Journal of Cancer Research and Therapeutics | Published by Wolters Kluwer - Medknow.

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