Moti, M. and Amini, L. and Ardakani, S.S.M. and Kamalzadeh, S. and Masoomikarimi, M. and Jafarisani, M. (2015) Oxidative stress and anti-oxidant defense system in Iranian women with polycystic ovary syndrome. Iranian Journal of Reproductive Medicine, 13 (6). pp. 373-378.
Full text not available from this repository.Abstract
Background: Polycystic ovary syndrome (PCOS) is a common disorder of infertility which affects more than 100 million women. It is characterized by chronic anovulation, hyper androgenism and obesity. PCOS is also associated with oxidative stress changes. Objective: Here, we aimed to investigate the level of antioxidants and oxidative stress in Iranian women with PCOS as a predictive factor for cardiovascular disease for the first time in Iran. Materials and Methods: In this cross sectional study 30 women with PCOS and 30 healthy women were included. C-reactive protein, serum insulin, advanced oxidation protein products, and level of total antioxidants status were measured from blood samples. Results: The levels of serum insulin, C-reactive protein, advanced oxidation protein productswere significantly increased in women with PCOS compared with healthy women but there was a decrease in level of total antioxidants status in PCOS women. Conclusion: These changes show that oxidative stress contributes to PCOS and the decrease of antioxidants leads to increase of oxidation products contributing to PCOS. © 2015, Research and Clinical Center for Infertitlity. All rights reserved.
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 17 |
| Depositing User: | eprints admin |
| Date Deposited: | 01 Jul 2018 07:35 |
| Last Modified: | 01 Jul 2018 07:35 |
| URI: | http://eprints.iums.ac.ir/id/eprint/5531 |
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