Conicity index and waist-to-hip ratio are superior obesity indices in predicting 10-year cardiovascular risk among men and women

Motamed, N. and Perumal, D. and Zamani, F. and Ashrafi, H. and Haghjoo, M. and Saeedian, F.S. and Maadi, M. and Akhavan-Niaki, H. and Rabiee, B. and Asouri, M. (2015) Conicity index and waist-to-hip ratio are superior obesity indices in predicting 10-year cardiovascular risk among men and women. Clinical Cardiology, 38 (9). pp. 527-534.

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Abstract

Background Central obesity has been recognized as a main risk factor for cardiovascular (CV) events. Three popular central obesity indices are waist circumference, waist-to-hip ratio (WHR), and waist-to-height ratio; abdominal volume index and conicity index are 2 recent novel obesity indices. The main aim of this study is to determine the performance of these indices to best predict 10-year CV events. Hypothesis Some obesity indices can be used to predict cardiovascular risk. Methods In total, 3199 subjects (age range, 40-79 years) were enrolled in this cross-sectional study. The American College of Cardiology/American Heart Association and Framingham risk score tools were used to estimate the 10-year CV events. Receiver operating characteristic curve analysis was used to determine the optimal discriminator(s) among the central obesity measures in the estimation of a 10-year risk of CV events �7.5, �10, and �20 separately. Results Among the 5 central obesity indices, conicity index showed the most discriminatory power in estimation of a 10-year CV risk. In men, based on the American College of Cardiology/American Heart Association tool, the areas under the curve (AUCs) were from 0.671 to 0.682 based on the 3 above thresholds, whereas with the Framingham tool, AUCs were from 0.651 to 0.659. In women, all AUCs were >0.7. Our results also showed WHR to be an almost comparable discriminator of CV disease risk in the Iranian study population. Conclusion Conicity index and WHR had a more discriminatory accuracy for 10-year CV events compared with the other obesity indices. © 2015 Wiley Periodicals, Inc.

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