Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews

Jafari, M. and Mousavi, S.M. and Asgharzadeh, A. and Yazdani, N. (2018) Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews. Indian Heart Journal, 70. S111-S117.

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Introduction: This article is an attempt to provide an overview of systematic reviews to determine the efficacy of CQ10 supplementation in the treatment of patients with cardiovascular diseases (CVD). Method and material: All reviews were identified through a systematic search of the following databases: Cochrane, DARE, Ovid, EMBASE, ISI Web of Knowledge, and PubMed. Check references studies and the quality of the studies was assessed by means of AMSTTAR. No meta-analyses were performed due to the heterogeneity of studies. Result: Extracted data for Seven systematic reviews for primary outcomes, net changes in cardiac output, cardiac index, New York Heart Association functional classification, improved survival, based on existing evidence, there is a case for use of CoQ10 as an adjunctive therapy in congestive heart failure, especially in those patients unable to tolerate mainstream medical therapies. Conclusion: Evidence suggests that the CoQ10 supplement may be a useful tool for managing patients with heart failure. © 2018

Item Type: Article
Additional Information: cited By 1
Subjects: WG Cardiovascular System
QV Pharmacology
Depositing User: eprints admin
Date Deposited: 01 Jan 2019 09:33
Last Modified: 15 Apr 2020 04:44

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