Aalaei-Andabili, S.H. and Beaver, T.M. and Petersen, J.W. and Anderson, R.D. and Karimi, A. and Thoburn, E. and Kabir, A. and Bavry, A.A. and Arnaoutakis, G.J. (2018) Early and midterm outcomes of transcatheter aortic valve replacement in patients with bicuspid aortic valves. Journal of Cardiac Surgery, 33 (9). pp. 489-496.
Full text not available from this repository.Abstract
Background: Bicuspid aortic valve (BAV) stenosis has been considered a relative contraindication to transcatheter aortic valve replacement (TAVR). We compared the outcomes of TAVR in patients with BAV stenosis versus patients with trileaflet aortic valve stenosis. Methods: From March 2012 to September 2017, 727 patients underwent TAVR. Thirty-two patients with BAV were included in this study and compared to 96 patients with comparable risk factors (1:3) with a trileaflet aortic valve (TAV). Transesophageal echocardiography was used to estimate post-TAVR degree of paravalvular leak (PVL). Results: Mean ± standard deviation Society of Thoracic Surgeons risk was 6.01 ± 3.42 in the BAV group and 6.08 ± 3.76 in the TAV group (P = 0.92). Thirty-day mortality was 4.2 (N = 4) in the TAV group and 6.25 (N = 2) in the BAV group (P = 0.63). Three (3.1) patients in the TAV group and two (6.25) patients in the BAV group developed a post operative stroke (P = 0.59). Following TAVR, mean aortic valve gradient significantly decreased in both TAV (42.56 ± 14.93 vs 9.27 ± 5.57, P < 0.001) and BAV (44.12 ± 11.82 vs 9.03 ± 7.29, P < 0.001) groups. No patient had a severe PVL after TAVR, and only two (2.08) patients in the TAV group and one (3.12) patient in the BAV group had moderate PVL (P = 1.0). Patient survival rate at 1 and 2 years was 86 in the BAV group and 90 at 1 and 2 years in the TAV group (P = 0.74). Conclusions: TAVR in BAV disease is feasible with favorable valve performance. Immediate and mid-term outcomes of TAVR in patients with BAV are comparable to those with TAV. © 2018 Wiley Periodicals, Inc.
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 0 |
| Subjects: | WG Cardiovascular System |
| Depositing User: | eprints admin |
| Date Deposited: | 24 Dec 2018 11:03 |
| Last Modified: | 19 Aug 2019 08:33 |
| URI: | http://eprints.iums.ac.ir/id/eprint/6254 |
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