Karamali, M. and Kashanian, M. and Alaeinasab, S. and Asemi, Z. (2018) The effect of dietary soy intake on weight loss, glycaemic control, lipid profiles and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome: a randomised clinical trial. Journal of Human Nutrition and Dietetics, 31 (4). pp. 533-543.
Full text not available from this repository.Abstract
Background: The present study aimed to evaluate the effects of dietary soy intake on weight loss and metabolic status of patients with polycystic ovary syndrome (PCOS). Methods: A randomised clinical trial was conducted among 60 women with PCOS. Participants were randomly assigned into two groups to receive either a test diet (n = 30) or a control diet (n = 30) for 8 weeks. Participants in the test group consumed a diet containing 0.8 g protein kg�1 body weight (35 animal proteins, 35 soy protein and 30 vegetable proteins) and participants in the control group consumed a similar diet containing 70 animal proteins and 30 vegetable proteins. Results: Adherence to the test diet, compared with the control diet, resulted in significant decreases mean (SD) in body mass index (BMI) �0.3 (0.6) versus +0.1 (0.5) kg m�2, P = 0.02, fasting plasma glucose �0.2 (0.5) versus +0.1 (0.3) mmol L�1, P = 0.01, total testosterone �0.3 (0.7) versus +0.3 (0.3) mmol L�1, P < 0.001, insulin �15.0 (18.0) versus +4.8 (18.6) pmol L�1, P < 0.001 and insulin resistance �0.6 (0.6) versus +0.2 (0.7), P < 0.001, as well as a significant increase in quantitative insulin sensitivity check index +0.01 (0.01) versus �0.002 (0.02), P = 0.01. In addition, significant decreases in triglycerides �0.1 (0.4) versus +0.2 (0.3) mmol L�1, P = 0.01 and malondialdehyde (MDA) �1.2 (1.0) versus +0.2 (1.2) μmol L�1, P < 0.001 and significant increases in nitric oxide (NO) +13.6 (14.1) versus +0.9 (24.3) μmol L�1, P = 0.01 and glutathione (GSH) +170.1 (175.5) versus +24.2 (168.7) μmol L�1, P = 0.002 were seen in the test group compared to the control. Conclusions: Adherence to test diet among subjects with PCOS significantly decreased BMI, glycaemic control, total testosterone, triglycerides and MDA, and significantly increased NO and GSH compared to the control diet. © 2018 The British Dietetic Association Ltd.
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 0 |
| Subjects: | WB Practice of Medicine WP Gynecology |
| Depositing User: | eprints admin |
| Date Deposited: | 24 Dec 2018 07:27 |
| Last Modified: | 24 Dec 2018 07:27 |
| URI: | http://eprints.iums.ac.ir/id/eprint/6335 |
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