Amirinia, C. and Seyedabadi, H.R. and Amirmozafari, N. and Torshizi, R.V. and Chamani, M. and Aliabad, A.J. and Abbasi, M.A. (2011) Association of transforming growth factor-�3 gene polymorphism with growth and body composition traits in Iranian commercial broiler lines. African Journal of Biotechnology, 10 (10). pp. 1784-1788.
Full text not available from this repository.Abstract
Transforming growth factor-β(TGF- β) polypeptides are members of a large superfamily of growth and differentiation factors that regulate the proliferation and differentiation of a great variety of cell types. The current study was designed to investigate the associations of TGF- β 3 gene polymorphism on chicken growth and body composition traits. Genomic DNAs were extracted from 400 chickens from four different commercial broiler lines. Genotyping for the TGF-β3 gene using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method and BslI restriction endonuclease showed a mutation in 294-bp fragment located on the fourth intron of chromosome 5. Polymorphism in TGF- β 3 gene was significantly (P < 0.1) associated with breast muscle weight (BMW), abdominal fat weight (AFW), wing weight (WINW), percentage of carcass weight (CW), percentage of drumstick weight (DW), percentage of breast muscle weight (BMW), percentage of back weight (BAKWT) and percentage of wing weight (WINW). This research suggests that TGF- β 3 gene could be a candidate gene that can affect some body composition traits in chicken. © 2011 Academic Journals.
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 2 |
| Uncontrolled Keywords: | genomic DNA; transforming growth factor beta3, abdominal fat; article; back; biological trait; body composition; breast; broiler; carcass; chromosome 5; controlled study; DNA polymorphism; forelimb; gene mutation; genotype; growth; intron; leg; muscle mass; nonhuman; nucleotide sequence, Gallus gallus |
| Subjects: | QU Biochemistry. Cell Biology and Genetics QW Microbiology. Immunology |
| Depositing User: | somayeh pourmorteza |
| Date Deposited: | 06 Jan 2019 06:51 |
| Last Modified: | 06 Jan 2019 06:51 |
| URI: | http://eprints.iums.ac.ir/id/eprint/7447 |
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