Chronic subclinical inflammation after phakic intraocular lenses implantation: Comparison between Artisan and Artiflex models

Hedayatfar, A. and Hashemi, H. and Asghari, S. and Badie, N. and Miraftab, M. (2017) Chronic subclinical inflammation after phakic intraocular lenses implantation: Comparison between Artisan and Artiflex models. Journal of Current Ophthalmology, 29 (4). pp. 300-304.


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Purpose To compare chronic subclinical inflammation induced after implantation of Artisan vs. Artiflex phakic intraocular lenses (pIOLs). Methods This prospective, comparative, non-randomized study included consecutive patients with moderate to high myopia who underwent Artisan or Artiflex pIOL implantation with standard surgery and postoperative care. Anterior chamber flare was assessed quantitatively using laser flare photometry (LFP) at baseline, 1 week, 1 month, 3 months, 6 months, and 2 years after surgery. Results PIOLs were implanted in 72 eyes (40 patients); Artisan pIOLs in 16 eyes (Artisan group) and Artiflex pIOLs in 56 eyes (Artiflex group). The mean preoperative anterior chamber flare was 6.5 ± 2.3 (range, 4.2�9.5) photons per millisecond (ph/ms) and 4.2 ± 0.9 (range, 2.5�11.7) ph/ms in Artisan and Artiflex groups, respectively (P = 0.400). In spite of early postoperative rise, the flare value returned to preoperative levels 6 months after pIOL implantation and remained stable up to 2 years. The amount of flare was not statistically different between Artisan and Artiflex groups in any postoperative follow-up (all P > 0.05). The trend in flare changes was not different between the studied groups (ANCOVA, P = 0.815). Conclusion The inflammatory response induced by implantation of either type of Artisan and Artiflex pIOLs is short-lived without statistically significant difference between the two models. © 2017 Iranian Society of Ophthalmology

Item Type: Article
Additional Information: cited By 1
Uncontrolled Keywords: prednisolone, adult; anterior eye chamber; Article; comparative study; controlled clinical trial; controlled study; female; follow up; high myopia; human; laser flare photometry; lens implantation; major clinical study; male; photometry; postoperative period; preoperative evaluation; prospective study; quantitative analysis; treatment outcome; uveitis; visual system examination
Subjects: WW Ophthalmology
Depositing User: eprints admin
Date Deposited: 01 Jan 2019 09:43
Last Modified: 19 Jun 2019 07:41

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