Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews

Jafari, M. and Mousavi, S.M. and Asgharzadeh, A. and Yazdani, N. (2018) Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews. Indian Heart Journal.

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Abstract

Introduction: This article is an attempt to provide an overview of systematic reviews to determine the efficacy of CQ10 supplementation in the treatment of patients with CVD. Method and material: All reviews were identified through a systematic search of the following databases: Cochrane, DARE, Ovid, EMBASE, ISI Web of Knowledge, and PubMed. Check references studies and the quality of the studies was assessed by means of AMSTTAR. No meta-analyses were performed due to the heterogeneity of studies. Result: Extracted data for Seven systematic reviews for primary outcomes, net changes in cardiac output, cardiac index, New York Heart Association functional classification, improved survival, based on existing evidence, there is a case for use of CoQ10 as an adjunctive therapy in congestive heart failure, especially in those patients unable to tolerate mainstream medical therapies. Conclusion: Evidence suggests that the CoQ10 supplement may be a useful tool for managing patients with heart failure. © 2018.

Item Type: Article
Additional Information: cited By 0; Article in Press
Subjects: WG Cardiovascular System
QU Biochemistry. Cell Biology and Genetics
Depositing User: eprints admin
Date Deposited: 01 Jul 2018 04:05
Last Modified: 03 Feb 2020 07:23
URI: http://eprints.iums.ac.ir/id/eprint/920

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