Portomesentric and splenic vein thrombosis (PMSVT) after bariatric surgery: a systematic review of 110 patients

Shoar, S. and Saber, A.A. and Rubenstein, R. and Safari, S. and Brethauer, S.A. and Al-Thani, H. and Asarian, A.P. and Aminian, A. (2018) Portomesentric and splenic vein thrombosis (PMSVT) after bariatric surgery: a systematic review of 110 patients. Surgery for Obesity and Related Diseases, 14 (1). pp. 47-59.

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Background Portomesenteric and splenic vein thrombosis (PMSVT) is a rare but potentially serious complication after bariatric surgery. No study has systematically analyzed its incidence and risk factors. Objectives To pool the data regarding PMSVT after bariatric surgery and determine its incidence and risk factors. Methods A meta-analysis and systematic review was conducted to retrieve studies on PMSVT after bariatric surgery. Results A total of 41 eligible studies including 110 patients with postbariatric PMSVT were enrolled; the estimated incidence rate based on 13 studies was.4. The use of oral contraception was reported in 35.4 of patients, previous surgery in 61.1, smoking in 37.2, and history of coagulopathy in 43. PMSVT mostly occurred after sleeve gastrectomy (78.9) and within the first postoperative month (88.9). Pneumoperitoneum pressure was>15 mm Hg in 6 of patients. The portal vein was the most commonly affected vessel (41.5). Prothrombin 20210 mutation and protein C/S deficiency were the most common thrombophilic conditions. Unfractionated heparin (59.1), vitamin K antagonists (50.9), and low molecular weight heparin (39.1) were the most common treatments for PMSVT. The morbidity and mortality rates for postbariatric PMSVT were 8.2 and 3.6, respectively. Conclusion PMSVT usually occurs within the first postoperative month and is mostly reported after sleeve gastrectomy. The portal vein is the most commonly involved vessel. A previous hypercoagulable state can be an important risk factor. Most patients can be treated with anticoagulation therapy. Further studies with comprehensive data review of patient information are required. © 2018 American Society for Bariatric Surgery

Item Type: Article
Additional Information: cited By 2
Depositing User: eprints admin
Date Deposited: 01 Jul 2018 03:54
Last Modified: 01 Jul 2018 03:54
URI: http://eprints.iums.ac.ir/id/eprint/997

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